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progeria

American  
[proh-jeer-ee-uh] / proʊˈdʒɪər i ə /

noun

Pathology.
  1. a rare congenital abnormality characterized by premature and rapid aging, the affected individual appearing in childhood as an aged person and having a shortened life span.


progeria British  
/ prəʊˈdʒɪərɪə /

noun

  1. med premature old age, a rare condition occurring in children and characterized by small stature, absent or greying hair, wrinkled skin, and other signs of old age

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of progeria

1900–05; < New Latin < Greek progḗr ( ōs ) prematurely old ( pro- pro- 2 + gêr ( as ) old age + -ōs adj. suffix) + New Latin -ia -ia

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

A research team led by Professor Chuanmao Zhang from Peking University and Kunming University of Science and Technology has long been focused on uncovering the biological mechanisms behind aging and progeria.

From Science Daily

Mekhail notes the discovery is also relevant to premature aging conditions like progeria.

From Science Daily

They also plan to model a disease called progeria, in which cells have a genetic mutation that leads to loss of heterochromatin.

From Science Daily

At age 3, just hours after the birth of the Kushners’ daughter, Aaron was diagnosed with a rare disease, progeria, in which the body ages rapidly.

From New York Times

Seidman says the team is encouraged by a recent success at using DNA base editing to repair heart cells and other kinds in mice with progeria, a disease that causes children to age rapidly.

From Science Magazine