[ proh-zak ]

Pharmacology, Trademark.

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Origin of Prozac

First recorded in 1988

Words Nearby Prozac Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

How to use Prozac in a sentence

British Dictionary definitions for Prozac


/ (ˈprəʊzæk) /

  1. trademark fluoxetine; a drug that prolongs the action of serotonin in the brain; used as an antidepressant

Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Cultural definitions for Prozac®


This widely used antidepressant drug works by modifying the behavior of neurotransmitters in the brain. It is the first of a series of psychoactive drugs that work in this way.

Notes for Prozac®

The high degree of effectiveness of Prozac in treating depression has spurred debate over whether such drugs should be used for milder problems, such as shyness, or even used simply to improve an otherwise normal mood.

Notes for Prozac®

References to Prozac are sometimes mildly derogatory, indicating a psychological state in which true feelings have been replaced by a drug-induced tranquility.

The New Dictionary of Cultural Literacy, Third Edition Copyright © 2005 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.