an antibody that is found in the blood of many persons afflicted with rheumatoid arthritis and that reacts against globulins in the blood.
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Origin of rheumatoid factor
First recorded in 1945–50
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019
Medicine definitions for rheumatoid factor
Any of the immunoglobulins found in the serum of individuals with rheumatoid arthritis that enhance the agglutination of suspended particles that are coated with pooled human gamma globulin and that are used to diagnose the disease.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.