schizophrenia

American  

[skit-suh-free-nee-uh, -freen-yuh] / ˌskɪt səˈfri ni ə, -ˈfrin jə /

noun

• schizophrenias
  plural

1. Formerly dementia praecox.  Psychiatry. a spectrum of mental disorders characterized by emotional blunting, intellectual deterioration, social isolation, disorganized speech and behavior, delusions, hallucinations, or a combination of any of these symptoms.

2. Sometimes Offensive. a state characterized by the coexistence of contradictory or incompatible elements.

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schizophrenia British  

/ ˌskɪtsəʊˈfriːnɪə /

noun

1. any of a group of psychotic disorders characterized by progressive deterioration of the personality, withdrawal from reality, hallucinations, delusions, social apathy, emotional instability, etc See catatonia hebephrenia paranoia

2. informal behaviour that appears to be motivated by contradictory or conflicting principles

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schizophrenia Scientific  

/ skĭt′sə-frē′nē-ə,skĭt′sə- /

1. Any of a group of psychiatric disorders characterized by withdrawal from reality, illogical patterns of thinking, delusions, hallucinations, and psychotic behavior. Schizophrenia is associated with an imbalance of the neurotransmitter dopamine in the brain and may have an underlying genetic cause.

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schizophrenia Cultural  

1. A form of psychosis marked by a strong tendency to dissociate oneself from reality. Schizophrenia is often characterized by hallucinations, delusions, and inappropriate reactions to situations. The word schizophrenia is often used informally as well as scientifically to indicate a split personality.

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Other Word Forms

Derived Forms

• nonschizophrenic
  adjective
• schizophrenic
  adjective
• unschizophrenic
  adjective

Inflected Forms

Nouns

• schizophrenias
  plural

Etymology

Origin of schizophrenia

First recorded in 1910–15; schizo- + -phrenia

Compare meaning

How does schizophrenia compare to similar and commonly confused words? Explore the most common comparisons:

• schizoid vs. schizophrenia

Explanation

Someone with a mental illness that's caused them to lose touch with reality and to withdraw from society may end up being diagnosed with schizophrenia, a serious disorder that can usually be treated with medication. A Swiss psychiatrist first came up with the term Schizophrenie, or "a splitting of the mind," to refer to the mental illness in 1910. A person with schizophrenia may feel and behave as if his mind has split off from reality, as he perceives things in a distorted way, and often speaks and acts in ways that appear bizarre. Sometimes schizophrenia is used to mean "inconsistent or contradictory."

Example Sentences

See Examples For:

schizophrenia schizophrenias

Compared with healthy participants, people with schizophrenia showed a pronounced and widespread reduction in synaptic connections across several parts of the brain.

From Science Daily ● Aug. 20, 2026

The scientists hope this will help shed light on how a range of disorders such as autism and schizophrenia first emerge and then progress later in life.

From Barron's ● Aug. 19, 2026

Some of the highest-paid amounts related to treatment of psychosis, schizophrenia and sepsis.

From Los Angeles Times ● Aug. 6, 2026

Many of its symptoms were virtually identical to the delusions of paranoid schizophrenia.

From The Wall Street Journal ● Jul. 28, 2026

Carlyle explains that schizoaffective is a cross between bipolar and schizophrenia.

From "Challenger Deep" by Neal Shusterman

Listen to people who live with the schizophrenias.

From The Verge ● Feb. 11, 2019

What are some of the stigmas the schizophrenias have, even within the world of mental illness?

From The Verge ● Feb. 11, 2019

He defined the disorder as a slow- developing illness without the hallucinations that are a classic element in the Western definition of many schizophrenias.

From Time Magazine Archive