[ skli-roh-sis ]
/ sklɪˈroʊ sɪs /
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noun, plural scle·ro·ses [skli-roh-seez]. /sklɪˈroʊ siz/.
Pathology. a hardening or induration of a tissue or part, or an increase of connective tissue or the like at the expense of more active tissue.
Botany. a hardening of a tissue or cell wall by thickening or lignification.
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Origin of sclerosis

1350–1400; Middle English <Medieval Latin <Greek sklḗrōsis hardening. See scler-, -osis


scle·ro·sal, adjective
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2022

How to use sclerosis in a sentence

British Dictionary definitions for sclerosis

/ (sklɪəˈrəʊsɪs) /

noun plural -ses (-siːz)
pathol a hardening or thickening of organs, tissues, or vessels from chronic inflammation, abnormal growth of fibrous tissue, or degeneration of the myelin sheath of nerve fibres, or (esp on the inner walls of arteries) deposition of fatty plaquesCompare arteriosclerosis, atherosclerosis, multiple sclerosis
the hardening of a plant cell wall or tissue by the deposition of lignin
a debilitating lack of progress or innovation within an institution or organization

Derived forms of sclerosis

sclerosal, adjective

Word Origin for sclerosis

C14: via Medieval Latin from Greek sklērōsis a hardening
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medical definitions for sclerosis

[ sklə-rōsĭs ]

n. pl. scle•ro•ses (-sēz)
The hardening of a tissue or part due to chronic inflammation.
A thickening or hardening of a body part or system especially from excessive formation of fibrous interstitial or glial tissue.
Any of various diseases characterized by thickening or hardening, such as arteriosclerosis.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.