Pathology. a hardening or induration of a tissue or part, or an increase of connective tissue or the like at the expense of more active tissue.
Botany. a hardening of a tissue or cell wall by thickening or lignification.
- scle·ro·sal, adjective
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
How to use sclerosis in a sentence
After Hurricane Florence in 2018, Gray went three days with no way to refrigerate medicine for her multiple sclerosis or pump the floodwater out of her basement.Longer, more frequent outages afflict the U.S. power grid as states fail to prepare for climate change | Douglas MacMillan, Will Englund | October 24, 2021 | Washington Post
Faustman’s colleagues in Italy, neurologists Marco Salvetti and Giovanni Ristori of Sapienza University of Rome, have been pursuing BCG as a treatment for multiple sclerosis since the late 1990s.
“Everybody kept getting signals, often from human data, saying this microorganism is doing beneficial things … whether it was allergy or autoimmunity or multiple sclerosis or diabetes.”
By this time, Faustman had met researchers from Rome who had found that BCG could reduce the likelihood that people with brain inflammation would develop multiple sclerosis — but the effect was most apparent after months to years.
She said she and her colleagues are studying B-cell and T-cell responses in vaccinated patients who have multiple sclerosis and other autoimmune neurological diseases.What immunosuppressed patients should know about the coronavirus vaccines | Lindsey Bever | April 23, 2021 | Washington Post
One of the plaintiffs is Melissa Davenport, a woman with multiple sclerosis.The Town Where Your Sex Toy Could Land You in Jail | Emily Shire, Lizzie Crocker | May 30, 2014 | THE DAILY BEAST
In 2000, a year after being diagnosed with multiple sclerosis, Montel Williams ditched his wife, Grace.Paula Broadwell, Eminem, & More Spurned Lovers Who Went Ballistic | Paula Froelich | November 15, 2012 | THE DAILY BEAST
She talked about her father, afflicted with multiple sclerosis, who nevertheless managed to support the family.
Dressage is a useful therapy for people with multiple sclerosis.Lay Off the Dressage Attacks on Mitt and Ann Romney’s Horse Rafalca | Michelle Cottle | August 3, 2012 | THE DAILY BEAST
She is presently wheelchair-bound by multiple sclerosis but suddenly in hope of parole someday, thanks to the Supreme Court.Families Decry Supreme Court Decision on Juvenile Life Without Parole | Michael Daly | June 26, 2012 | THE DAILY BEAST
One of the most characteristic symptoms of old age is the hardening of the arteries—arterio-sclerosis.Life of Elie Metchnikoff, 1845-1916 | Olga Metchnikoff
This gentleman pronounced the case one of spinal (either multiple or posterior) sclerosis, and discarded the syphilitic theory.The Electric Bath | George M. Schweig
High tension and sclerosis of the radial artery were respectively found in about one-half of the cases.The Lettsomian Lectures 1900-1901 | J. Mitchell Bruce
It also occurs in patients suffering from glycosuria, and is usually associated with arterio-sclerosis—local or general.Manual of Surgery | Alexis Thomson and Alexander Miles
This type of sclerosis preceding death of the bone is highly characteristic of tuberculosis.Manual of Surgery | Alexis Thomson and Alexander Miles
British Dictionary definitions for sclerosis
pathol a hardening or thickening of organs, tissues, or vessels from chronic inflammation, abnormal growth of fibrous tissue, or degeneration of the myelin sheath of nerve fibres, or (esp on the inner walls of arteries) deposition of fatty plaques: Compare arteriosclerosis, atherosclerosis, multiple sclerosis
the hardening of a plant cell wall or tissue by the deposition of lignin
a debilitating lack of progress or innovation within an institution or organization
- sclerosal, adjective
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012