atherosclerosis

American  

[ath-uh-roh-skluh-roh-sis, ath-] / ˌæθ ə roʊ skləˈroʊ sɪs, ˌæð- /

noun

Pathology.

1. a common form of arteriosclerosis in which fatty substances form a deposit of plaque on the inner lining of arterial walls.

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atherosclerosis British  

/ ˌæθərəʊsklɪəˈrəʊsɪs, ˌæθərəʊsklɪəˈrɒtɪk /

noun

1. a degenerative disease of the arteries characterized by patchy thickening of the inner lining of the arterial walls, caused by deposits of fatty material; a form of arteriosclerosis See atheroma

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atherosclerosis Scientific  

/ ăth′ə-rō-sklə-rō′sĭs /

1. A form of arteriosclerosis characterized by the deposition of plaques containing cholesterol and lipids on the innermost layer of the walls of large- and medium-sized arteries. Individuals with atherosclerosis have a higher risk of coronary artery disease and stroke. Smoking, high blood pressure, diabetes mellitus, and elevated levels of fat in the blood contribute to the development of atherosclerosis.

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atherosclerosis Cultural  

1. A form of arteriosclerosis in which the arteries become clogged by the buildup of fatty substances, which eventually reduces the flow of blood to the tissues. These fatty substances, called plaque, are made up largely of cholesterol. (Compare arteriosclerosis; see circulatory system.)

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Other Word Forms

• atherosclerotic adjective
• atherosclerotically adverb

Etymology

Origin of atherosclerosis

1905–10; < German Atherosklerose; athero-, sclerosis

Compare meaning

How does atherosclerosis compare to similar and commonly confused words? Explore the most common comparisons:

• atherosclerosis vs. arteriosclerosis

Example Sentences

The results come from a subgroup analysis of the VESALIUS-CV randomized trial, funded by Amgen Inc. Researchers studied 3,655 patients who had high-risk diabetes but no significant atherosclerosis.

From Science Daily • Mar. 30, 2026

The process of atherosclerosis — the slow buildup of plaques on the artery walls that can lead to heart attacks, strokes and other events — begins long before symptoms occur.

From MarketWatch • Mar. 19, 2026

The combined findings reveal a serious gap in prevention: people who appear healthy according to standard assessments may already have significant and silent atherosclerosis.

From Science Daily • Nov. 27, 2025

In their paper published in Environment International, Zhou and colleagues describe their use of LDLR-deficient mice, a common model for examining atherosclerosis.

From Science Daily • Nov. 18, 2025

With 30 million Americans in this category, it has become one of the nation's chief health problems, and it is the predisposing factor in many other diseases such as heart trouble, diabetes, hypertension and atherosclerosis.

From A Practical Guide to Self-Hypnosis by Powers, Melvin