self-antigen
Americannoun
Etymology
Origin of self-antigen
First recorded in 1970–75
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
“Basically, you need three ingredients: self-antigen, an inflammatory environment and autoimmune predisposition,” he says.
From Scientific American ● Sep. 14, 2021
In peripheral tolerance, functional, mature B cells leave the bone marrow but have yet to be exposed to self-antigen.
From Textbooks ● Jun. 19, 2013
One explanation for the breakdown of tolerance is that, after certain bacterial infections, an immune response to a component of the bacterium cross-reacts with a self-antigen.
From Textbooks ● Jun. 19, 2013
The reason for this association is likely because if one’s MHC molecules are not able to present a certain self-antigen, then that particular autoimmune disease cannot occur.
From Textbooks ● Jun. 19, 2013
As T and B cells mature, there are mechanisms in place that prevent them from recognizing self-antigen, preventing a damaging immune response against the body.
From Textbooks ● Jun. 19, 2013
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