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sickle cell trait

noun

, Pathology.
  1. the usually asymptomatic hereditary condition that occurs when a person inherits from only one parent the abnormal hemoglobin gene characteristic of sickle cell anemia.


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Word History and Origins

Origin of sickle cell trait1

First recorded in 1925–30
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Example Sentences

Scientist Errol Morrison and author Patrick Cooper's controversial hypothesis, published in the West Indian Medical Journal,, external was that the prevalence of sickle cell trait - a mutation that causes round, red, oxygen-carrying blood cells to curl up in a sickle shape - among people of West African origin had "triggered a series of physiological adjustments, which, incidentally, had favourable athletic consequences".

From BBC

The disease, which can stunt physical growth, is more common in malaria-prone regions, notably Africa and India, because carrying the sickle cell trait helps protect against severe malaria.

Even a common test used to manage diabetes can underestimate blood sugar levels for patients who have sickle cell trait, which is present in nearly 1 in 10 African Americans.

It’s more common in malaria-prone regions because carrying the sickle cell trait helps protect against severe malaria.

Scientists believe being a carrier of the sickle cell trait helps protect against severe malaria, so the disease occurs more often in mosquito-prone regions such as Africa or in people whose ancestors lived in those places.

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