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simvastatin

American  
[sim-vuh-stat-n, sim-vuh-stat-n] / ˌsɪm vəˈstæt n, ˈsɪm vəˌstæt n /

noun

Pharmacology.
  1. a statin, C 25 H 38 O 5, used in the prevention and treatment of heart disease.


Etymology

Origin of simvastatin

First recorded in 1985–90;  sim-, possibly alteration of syn(thetic), + (lo)vastatin

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

The images showed that a commonly prescribed statin, simvastatin, binds to two specific sites on a muscle protein known as the ryanodine receptor.

From Science Daily Jan. 14, 2026

“Similarly, grapefruit juice has a well-established interaction with both simvastatin and lovastatin that can lead to myopathy or rhabdomyolysis. Eating a grapefruit instead of drinking the juice will not avoid the interaction.”

From Washington Post Dec. 3, 2021

In the early 1990s, the Scandinavian Simvastatin Survival Study showed that the statin simvastatin was effective at lowering LDL cholesterol and reducing the risk of a heart attack4.

From Scientific American Dec. 2, 2021

My prescriptions include metformin, glimepiride, simvastatin and losartan.

From Seattle Times Oct. 27, 2021

The high, daily dose of simvastatin was well tolerated and slowed brain shrinkage by 43% over two years compared with the placebo.

From BBC Mar. 19, 2014

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