simvastatin

[sim-vuh-stat-n, sim-vuh-stat-n]

noun

Pharmacology.

1. a statin, C 25 H 38 O 5, used in the prevention and treatment of heart disease.

Word History and Origins

Origin of simvastatin¹

First recorded in 1985–90;  sim-, possibly alteration of syn(thetic), + (lo)vastatin

Example Sentences

People taking simvastatin were 22% less likely to have a stroke.

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I am currently on the same hospital's MS-STAT2 simvastatin trial, testing whether a high-dose statin can limit brain atrophy in MS.

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“Similarly, grapefruit juice has a well-established interaction with both simvastatin and lovastatin that can lead to myopathy or rhabdomyolysis. Eating a grapefruit instead of drinking the juice will not avoid the interaction.”

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In the early 1990s, the Scandinavian Simvastatin Survival Study showed that the statin simvastatin was effective at lowering LDL cholesterol and reducing the risk of a heart attack4.

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It has already been established that simvastatin may help slow the rate at which the brain shrinks in MS, and so perhaps slow the progression of disability.

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