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simvastatin

American  
[sim-vuh-stat-n, sim-vuh-stat-n] / ˌsɪm vəˈstæt n, ˈsɪm vəˌstæt n /

noun

Pharmacology.
  1. a statin, C 25 H 38 O 5, used in the prevention and treatment of heart disease.


Etymology

Origin of simvastatin

First recorded in 1985–90;  sim-, possibly alteration of syn(thetic), + (lo)vastatin


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

The images showed that a commonly prescribed statin, simvastatin, binds to two specific sites on a muscle protein known as the ryanodine receptor.

From Science Daily ● Jan. 14, 2026

“Similarly, grapefruit juice has a well-established interaction with both simvastatin and lovastatin that can lead to myopathy or rhabdomyolysis. Eating a grapefruit instead of drinking the juice will not avoid the interaction.”

From Washington Post ● Dec. 3, 2021

My prescriptions include metformin, glimepiride, simvastatin and losartan.

From Seattle Times ● Oct. 27, 2021

The high, daily dose of simvastatin was well tolerated and slowed brain shrinkage by 43% over two years compared with the placebo.

From BBC ● Mar. 19, 2014

FDA’s safety warning that 80 mg simvastatin is linked to myopathy, issued on June 8, 2011, struck a chord in me because the 80 mg dose of simvastatin was the same given my mother.

From Scientific American ● Jun. 30, 2011

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