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substrate

American  
[suhb-streyt] / ˈsʌb streɪt /

noun

  1. a substratum.

  2. Biochemistry. the substance acted upon by an enzyme.

  3. Electronics. a supporting material on which a circuit is formed or fabricated.


substrate British  
/ ˈsʌbstreɪt /

noun

  1. biochem the substance upon which an enzyme acts

  2. another word for substratum

  3. electronics the semiconductor base on which other material is deposited, esp in the construction of integrated circuits

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

substrate Scientific  
/ sŭbstrāt′ /
  1. The material or substance on which an enzyme acts.

  2. See more at enzyme

  3. The surface on or in which plants, algae, or certain animals, such as barnacles or clams, live or grow. A substrate may serve as a source of food for an organism or simply provide support.


Etymology

Origin of substrate

First recorded in 1570–80; variant of substratum

Explanation

A substrate is the base layer of something, or a layer that's underneath another layer. It can also be a surface on which an organism grows or is attached. Substrate also has a linguistic meaning: It's an indigenous language that contributes words or parts of speech to the language of an invading people who have imposed their language on the indigenous people. Throughout the United States, for instance, there are towns with Native American names, because Native American languages form a substrate to American English.

Keep Reading on Vocabulary.com

Vocabulary lists containing substrate

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

The industry’s move to co-packaged optics — where optical transceivers are integrated directly onto the chip substrate to save power — will be an especially big benefit to Lumentum.

From MarketWatch • Mar. 18, 2026

A water system irrigates the plants via a nutrient substrate, a liquid fertiliser that replaces the nutrients and minerals naturally present in the soil.

From Barron's • Feb. 17, 2026

As a core second-tier supplier to Nvidia, Kinsus has also decided to expand ABF substrate production capacity.

From The Wall Street Journal • Feb. 2, 2026

It continues to play a critical supporting role amid a shortage of high-end substrate capacity, and is a key backup supplier to Nvidia for legacy products, the analysts say.

From The Wall Street Journal • Feb. 2, 2026

And that there exists a pure consciousness devoid of substrate and objects alike, we have already refuted on the ground that of a thing of this kind we have absolutely no knowledge.

From The Vedanta-Sutras with the Commentary by Ramanuja — Sacred Books of the East, Volume 48 by Thibaut, George