of or relating to a system.
Physiology, Pathology.
  1. pertaining to or affecting the body as a whole.
  2. pertaining to or affecting a particular body system.
(of a pesticide) absorbed and circulated by a plant or other organism so as to be lethal to pests that feed on it.

Origin of systemic

First recorded in 1795–1805; system + -ic
Related formssys·tem·i·cal·ly, adverbnon·sys·tem·ic, adjective
Can be confusedsystematic systemic Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

Examples from the Web for systemic

Contemporary Examples of systemic

Historical Examples of systemic

British Dictionary definitions for systemic



physiol (of a poison, disease, etc) affecting the entire body
(of a pesticide, fungicide, etc) spreading through all the parts of a plant and making it toxic to pests or parasites without destroying it


a systemic pesticide, fungicide, etc
Derived Formssystemically, adverb
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for systemic

1803, irregularly formed from system, used in medicine and biology for differentiation of meaning from systematic. Related: Systemically.

Online Etymology Dictionary, © 2010 Douglas Harper

systemic in Medicine




Of or relating to a system.
Of, relating to, or affecting the entire body or an entire organism.
Relating to or affecting a particular body system, especially the nervous system.
Relating to systemic circulation.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.