Dictionary.com
Thesaurus.com
Synonyms

systemic

American  
[si-stem-ik] / sɪˈstɛm ɪk /

adjective

  1. of or relating to a system, especially when affecting the entirety of a thing.

    systemic flaws in the design and construction of the vehicles.

  2. relating to or noting a policy, practice, or set of beliefs that has been established as normative or customary throughout a political, social, or economic system: systemic racism.

    systemic inequality;

    systemic racism.

  3. Physiology, Pathology.

    1. relating to or affecting the body as a whole.

    2. relating to or affecting a particular body system.

  4. (of a pesticide) absorbed and circulated by a plant or other organism so as to be lethal to pests that feed on it.


systemic British  
/ -ˈstiː-, sɪˈstɛmɪk /

adjective

  1. another word for systematic systematic

  2. physiol (of a poison, disease, etc) affecting the entire body

  3. (of a pesticide, fungicide, etc) spreading through all the parts of a plant and making it toxic to pests or parasites without destroying it

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

noun

  1. a systemic pesticide, fungicide, etc

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of systemic

First recorded in 1795–1805; system + -ic

Explanation

Something that's systemic affects all parts of something. If every dog at doggy daycare has fleas, it's a systemic problem. The adjective systemic is often used to describe diseases or disorders; a systemic illness affects your whole body or an entire system — like your digestive system. Any kind of system can experience systemic problems. For example, crime is a systemic problem in a community because it affects everyone from individuals to families, businesses, and tourism, just to name a few groups harmed by the problem.

Keep Reading on Vocabulary.com

Vocabulary lists containing systemic

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Eradicating corruption "is a matter of our capability to survive," Fedorov said, adding "we have a systemic crisis of governance."

From Barron's Aug. 19, 2026

By contrast, p-cresol sulfate and phenol sulfate come from tyrosine and have been linked to worse outcomes in cancer patients as well as systemic toxicity in people with kidney disease.

From Science Daily Aug. 15, 2026

Teaming them up as a testy odd couple allows “Lanterns” to both highlight Hal’s insecurity and use the Green Lantern universe’s rules to interrogate systemic imbalances.

From Salon Aug. 14, 2026

The initiative was approved by the Board of Supervisors in 2016 as a temporary way to analyze systemic issues that cause inequitable gender treatment and outcomes, and identify responses to help address those concerns.

From Los Angeles Times Aug. 11, 2026

What may have looked like separate events were all evidence of seismic and systemic social change.

From "1919 The Year That Changed America" by Martin W. Sandler

Vocabulary.com logo
by dictionary.com

Join 12,000,000 vocabulary learners

Start learning new words today on VocabTrainer.
You'll remember them forever.

Start training