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transcriptase

American  
[tran-skrip-teys, -teyz] / trænˈskrɪp teɪs, -teɪz /

noun

Biochemistry.
  1. RNA polymerase.


transcriptase British  
/ trænˈskrɪpteɪz /

noun

  1. See reverse transcriptase

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of transcriptase

First recorded in 1963; transcript(ion) + -ase

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Islatravir, meanwhile, is what’s known as a nucleoside reverse transcriptase translocation inhibitor, a novel drug that is significantly more potent.

From Barron's Feb. 25, 2026

While both drugs target the HIV-1 reverse transcriptase enzyme to prevent viral replication, they do so through entirely different biochemical pathways.

From Barron's Feb. 25, 2026

Finally, in 1975, with Howard Temin, a friend and colleague who had discovered reverse transcriptase around the same time, Baltimore was awarded the Nobel Prize for physiology or medicine.

From Los Angeles Times Sep. 8, 2025

One component is the prime editor, which combines a SpCas9 protein, used in the first CRISPR-Cas gene editing technology, and a reverse transcriptase, an enzyme that transcribes RNA into DNA.

From Science Daily May 29, 2024

Reverse transcription never occurs in uninfected host cells—the needed enzyme reverse transcriptase is only derived from the expression of viral genes within the infected host cells.

From Textbooks Jun. 9, 2022

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