1. (in some American Indian tribes) a person, especially a biological male, who adopts the gender identity, dress, and social roles traditionally assigned to the opposite sex.
  2. a person who adopts some combination of male and female gender identity, dress, and social roles, or who identifies as gay, lesbian, transgender, etc.
  3. a culturally distinct gender apart from the male and female gender.
Related formstwo-spirit·ed, adjective Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018