- to implant (a disease agent or antigen) in a person, animal, or plant to produce a disease for study or to stimulate disease resistance.
- to affect or treat (a person, animal, or plant) in this manner.
- to introduce (microorganisms) into surroundings suited to their growth, as a culture medium.
- to imbue (a person), as with ideas.
- Metallurgy. to treat (molten metal) chemically to strengthen the microstructure.
- to perform inoculation.
Origin of inoculate
SynonymsSee more synonyms on Thesaurus.com
Examples from the Web for inoculate
The commander of the Continental Army realized that if he did not inoculate his army against smallpox, he might not have an army.George Washington, the First Vaxxer
October 5, 2014
But even before adults enter their senior years, children are not a surefire way to inoculate against loneliness.Why Parents Can Still End Up Lonely
June 9, 2014
The ensuing hysteria persuaded some parents not to inoculate their kids for fear of triggering autism.Twitter Crushes Anti-Vaccination Queen Jenny McCarthy
The Daily Beast
March 15, 2014
A deeply-held belief in moral integrity does not inoculate one from mistakes, weakness and failure.Petraeus Affair Stereotypes: The General, The Flirt And The Harlot
November 15, 2012
First, the two sides understood that minimal advance assurances were needed to inoculate the meeting against a debacle.Winston Lord and Leslie H. Gelb: Nixon’s China Opening, 40 Years Later
Winston Lord, Leslie H. Gelb
February 20, 2012
Can we not inoculate them with smallpox, or set bloodhounds to track them?Canada: the Empire of the North
Agnes C. Laut
We inoculate in him a bad spirit whose effects then turn against us.The Simple Life
But it was decided to divide them into two equal groups, and inoculate one group.Experiments on Animals
It costs considerable, but a little of it will inoculate a large area.The Foolish Almanak
Formerly it was the custom to inoculate with small-pox to preserve from small-pox.Louis Pasteur
- to introduce (the causative agent of a disease) into the body of (a person or animal), in order to induce immunity
- (tr) to introduce (microorganisms, esp bacteria) into (a culture medium)
- (tr) to cause to be influenced or imbued, as with ideas or opinions
Word Origin and History for inoculate
mid-15c., "implant a bud into a plant," from Latin inoculatus, past participle of inoculare "graft in, implant," from in- "in" (see in- (2)) + oculus "bud," originally "eye" (see eye (n.)). Meaning "implant germs of a disease to produce immunity" first recorded (in inoculation) 1714, originally in reference to smallpox. After 1799, often used in sense of "to vaccine inoculate." Related: Inoculated; inoculating.
- To introduce a serum, a vaccine, or an antigenic substance into the body of a person or an animal, especially as a means to produce or boost immunity to a specific disease.
- To implant microorganisms or infectious material into or on a culture medium.
- To communicate a disease to a living organism by transferring its causative agent into the organism.
- The introduction of a serum, a vaccine, or an antigenic substance into the body of a person or an animal, especially as a means to produce or boost immunity to a specific disease.
- The introduction of a microorganism or an agent of disease into an host organism or a growth medium.