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-cule1

  1. variant of -cle1: animalcule; molecule; reticule.
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Origin of -cule1

(< F) < Latin -culus, -cula, -culum; see -cle1

-cule2

  1. variant of -cle2: ridicule.
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Origin of -cule2

(< F) < Latin -culum, -cula; see -cle2
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

British Dictionary definitions for -cule

-cule

suffix forming nouns
  1. indicating smallnessanimalcule
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Word Origin

from Latin -culus, diminutive suffix; compare -cle
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for -cule

word-forming element used to make diminutives, from French -cule or directly from Latin -culus (masc.), -cula (fem.), -culum (neuter).

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Online Etymology Dictionary, © 2010 Douglas Harper