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variant of -megaly: cardiomegalia.
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Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2023


What does -megalia mean?

The combining form -megalia is used like a suffix meaning “irregular enlargement” of an organ or part of the body. It appears in a few medical terms, especially in pathology.

The form -megalia ultimately comes from the Greek mégas, meaning “great, large.”

The form –megalia is a less-common variant of -megaly.

Want to know more? Read our Words That Use -megaly article.

Corresponding forms of -megalia and -megaly combined to the beginning of words is megalo- and megal-. Learn more at our Words That Use articles for the forms.

A variant of megalo- that you may be familiar with is mega-, as in megaphone or megabyte. Mega- is also used as a unit of measure prefix to indicate a fact of one million (e.g., megahertz).

Examples of -megalia

One of the few terms that features the combining form -megalia is splenomegalia, more commonly referred to as splenomegaly. Splenomegalia is “enlargement of the spleen.”

The combining form spleno- means “spleen.” The second part of the word, -megalia, means “irregular enlargement.” Splenomegalia literally translates to “irregularly large spleen.”

What are some words that use the combining form -megalia?

What are some other forms that -megalia may be commonly confused with?

Break it down!

The combining form cardio- means “heart.” What does the medical condition cardiomegalia, more commonly known as cardiomegaly, involve?

How to use -megalia in a sentence