genome
Americannoun
noun
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the full complement of genetic material within an organism
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all the genes comprising a haploid set of chromosomes
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The total amount of genetic information in the chromosomes of an organism, including its genes and DNA sequences. The genome of eukaryotes is made up of a single, haploid set of chromosomes that is contained in the nucleus of every cell and exists in two copies in all cells except reproductive and red blood cells. The human genome is made up of about 20,000 to 25,000 genes.
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Compare proteome
Other Word Forms
- genomic adjective
Etymology
Origin of genome
First recorded in 1925–30; from German Genom, from Gen gene + (Chromos)om chromosome
Explanation
The human genome is the map of your DNA, the double helix that contains all your genes. Your genome is all the genetic material contained in your 23 pairs of chromosomes, a total of more than 20,000 genes. Every organism has its own unique genome. "The Human Genome Project," completed in 2003, was an international effort to identify all the genes in human DNA and to determine the sequences of the 3 billion (yes, billion) base pairs — the smaller units that make up DNA. It took 13 years. Genome research has helped diagnose disease and find genetic markers for certain diseases.
Vocabulary lists containing genome
This Week In Words: March 29–April 4, 2020
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Genetics - Middle School
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Life Science: Genetics and Evolution
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Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
The groundbreaking genome sequencing is from a Barbary macaque called Crinkle at Trentham Monkey Forest, Stoke-on-Trent.
From BBC • Apr. 7, 2026
The past quarter-century has hosted a dizzying array of innovation, as the cutting edge of technology moved from Palm Pilots and flip phones to mobile internet, artificial intelligence, genome sequencing and so much more.
From The Wall Street Journal • Apr. 6, 2026
"And cancer is potentially exploiting that same principle, changing where in the genome these dynamics are more important to manipulate cell identity and encourage uncontrolled growth."
From Science Daily • Mar. 31, 2026
Following the chatbots' advice, he paid $3,000 to have Rosie's genome sequenced, and used the same online tools to analyse her DNA data.
From Barron's • Mar. 30, 2026
Inside every nucleus within each cell in your body, there’s an identical copy of your entire genome.
From "The Immortal Life of Henrietta Lacks" by Rebecca Skloot
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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.