genome
Americannoun
noun
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the full complement of genetic material within an organism
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all the genes comprising a haploid set of chromosomes
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The total amount of genetic information in the chromosomes of an organism, including its genes and DNA sequences. The genome of eukaryotes is made up of a single, haploid set of chromosomes that is contained in the nucleus of every cell and exists in two copies in all cells except reproductive and red blood cells. The human genome is made up of about 20,000 to 25,000 genes.
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Compare proteome
Other Word Forms
Derived Forms
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Nouns
Etymology
Origin of genome
First recorded in 1925–30; from German Genom, from Gen gene + (Chromos)om chromosome
Explanation
The human genome is the map of your DNA, the double helix that contains all your genes. Your genome is all the genetic material contained in your 23 pairs of chromosomes, a total of more than 20,000 genes. Every organism has its own unique genome. "The Human Genome Project," completed in 2003, was an international effort to identify all the genes in human DNA and to determine the sequences of the 3 billion (yes, billion) base pairs — the smaller units that make up DNA. It took 13 years. Genome research has helped diagnose disease and find genetic markers for certain diseases.
Vocabulary lists containing genome
This Week In Words: March 29–April 4, 2020
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Genetics - Middle School
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Life Science: Genetics and Evolution
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Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
See Examples For:
Department of Energy jointly announced that they had completed the sequencing of the human genome, which could ultimately unlock the mysteries of human health.
From The Wall Street Journal ● Jun. 26, 2026
These symptoms resemble those seen in certain human disorders linked to genome instability that affect the cerebellum.
From Science Daily ● Jun. 21, 2026
In contrast, the DNA breaks in neurons were concentrated mainly in regions of the genome that are not actively involved in critical gene functions.
From Science Daily ● Jun. 21, 2026
Traditional approaches often depend on comparing a polyploid genome with known diploid ancestors.
From Science Daily ● Jun. 19, 2026
Built into every genome, then, are the codes for proteins that will allow that genome to reproduce.
From "The Gene" by Siddhartha Mukherjee
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The team developed a bioinformatic framework capable of reconstructing the evolutionary history of complex polyploid genomes.
From Science Daily ● Jun. 19, 2026
"This work demonstrates how transposable elements can function as evolutionary time stamps embedded in plant genomes," said one of the study's senior authors.
From Science Daily ● Jun. 19, 2026
The framework follows genome evolution across three broad stages: before ancestral species diverged, during their separate evolutionary histories, and after their genomes merged.
From Science Daily ● Jun. 19, 2026
When applied to the cultivated octoploid strawberry, the technique revealed a step-by-step evolutionary history shaped by multiple rounds of allopolyploidization, providing new insight into how complex plant genomes form and diversify over millions of years.
From Science Daily ● Jun. 19, 2026
Our genomes are catalogues of instructions from all kinds of sources in nature, filed for all kinds of contingencies.
From "The Lives of a Cell" by Lewis Thomas
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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.