Parkinson's disease

Or Parkinson disease

noun

Pathology.

1. a common neurologic disease believed to be caused by deterioration of the brain cells that produce dopamine, occurring primarily after the age of 60, characterized by tremors, especially of the fingers and hands, muscle rigidity, shuffling gait, slow speech, and a masklike facial expression.

Parkinson's disease

/ ˈpɑːkɪnsənz /

noun

1. Also called: Parkinsonism.  Parkinson's syndrome.  paralysis agitans.  shaking palsy. Often shortened to: Parkinson's. a progressive chronic disorder of the central nervous system characterized by impaired muscular coordination and tremor

Parkinson's disease

1. A progressive neurologic disease occurring most often after the age of 50, associated with the destruction of brain cells that produce dopamine. Individuals with Parkinson's disease exhibit tremors while at rest, slowing of movement, stiffening of gait and posture, and weakness. The disease is named after its discoverer, British physician and paleontologist James Parkinson (1755–1824).

Parkinson's disease

1. A chronic disease of the nervous system that usually strikes in late adult life, resulting in a gradual decrease in muscle control. Symptoms of the disease include shaking, weakness, and partial paralysis of the face. Certain drugs can help alleviate some of its symptoms.

Word History and Origins

Origin of Parkinson's disease¹

Named after James Parkinson (1755–1824), English physician who first described it

Word History and Origins

Origin of Parkinson's disease¹

C19: named after James Parkinson (1755–1824), British surgeon, who first described it

Example Sentences

His latter years were blighted by maladies, including heart problems, Parkinson’s disease, and memory and hearing loss.

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The former Black Sabbath frontman, who was diagnosed with Parkinson's disease in 2019, died on 22 July.

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While Hunter syndrome represents a relatively small commercial opportunity, Denali has a clinical and preclinical pipeline of assets leveraging this technology, including for Sanfilippo syndrome—where the FDA has granted an accelerated approval path—Fabry disease, Parkinson’s disease, and Alzheimer’s disease, among others.

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In Parkinson's disease, this protein sticks together into toxic clumps that cause nerve cell death and leads to patients suffering from symptoms such as tremors, difficulties moving and muscle stiffness.

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Researchers at the University of Bath, in collaboration with the Universities of Oxford and Bristol, have developed a molecule that prevents the clumping and build-up of a protein linked to Parkinson's disease and related dementias.

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