amikacin

[am-i-key-sin]

noun

Pharmacology.

1. a broad-spectrum, semisynthetic, aminoglycoside antibiotic, C 22 H 45 N 5 O 13 , derived from kanamycin and used in the treatment of infections, especially those caused by Gram-negative bacilli.

Word History and Origins

Origin of amikacin¹

First recorded in 1970–75; perhaps ami(noglycoside) ( def. ) + ka(namy)cin ( def. )

Example Sentences

The COE in this study proved more effective than antibiotic controls amikacin and imipenem at eradicating Mab in both in-vitro and in-vivo experiments.

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Doctors discontinued the Amikacin and switched drugs.

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Because Amikacin can cause permanent hearing loss, she would need to undergo a hearing test every two weeks.

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William Hanage, an epidemiologist at the Harvard School of Public Health, was among those showing that these genes conferred a resistance to amikacin, a semi-synthetic drug that did not exist before the 1970s.

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Finally, XDR-TB is resistant to those two drugs, plus any fluoroquinolone and at least one of the three injectable second-line drugs, capreomycin, kanamycin and amikacin.

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