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antagonize

American  
[an-tag-uh-nahyz] / ænˈtæg əˌnaɪz /
especially British, antagonise

verb (used with object)

  • antagonizes,
    present (3rd person singular)
  • antagonized,
    past participle,  past
  • antagonizing
    present participle
  1. to make hostile or unfriendly; make an enemy or antagonist of.

    His speech antagonized many voters.

  2. to act in opposition to; oppose.


verb (used without object)

  • antagonizes,
    present (3rd person singular)
  • antagonized,
    past participle,  past
  • antagonizing
    present participle
  1. Rare. to act antagonistically.

antagonize British  
/ ænˈtæɡəˌnaɪz /

verb

  1. to make hostile; annoy or irritate

  2. to act in opposition to or counteract

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

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Etymology

Origin of antagonize

First recorded in 1625–35, antagonize is from the Greek word antagōnízesthai to contend against, dispute with. See ant-, agonize

Explanation

To antagonize is to provoke someone to react angrily. If your mother tells you to stop antagonizing your brother, she's asking you to stop making him mad. Antagonize shares the same Greek roots with the word agony, so think about how much agony you cause your siblings when you tease and goad them into getting angry. Bugs Bunny is known to antagonize Elmer Fudd, who hunts but never does catch that wabbit. Actually Bugs antagonizes every cartoon character he comes into contact with! In English class, you'll often be asked to name the antagonist of a story or novel, the character who provokes the main character to act.

Keep Reading on Vocabulary.com

Vocabulary lists containing antagonize

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

After consulting with his advisers, the Saudi crown prince told Trump that the effort was going to antagonize Iran and that it should be reconsidered, according to people familiar with the conversations.

From The Wall Street Journal Jul. 1, 2026

The former official asked not to be named because they work in public health and don’t want to antagonize the current administration.

From Salon Apr. 4, 2026

So that’s where Stroup and Bourne were in December 1977: entrenched in their positions, confident in their success, and unafraid to antagonize their opponents.

From Slate Dec. 23, 2025

“When we are fighting for our survival, we can’t afford to antagonize either Biden or Trump,” Mr. Merezhko said.

From New York Times Apr. 19, 2024

His tactic had been not to file any motions so as not to antagonize the jury.

From "The Stranger" by Albert Camus

“He antagonizes me on Twitter,” he said to a bystander, in an attempt to pass me off a second time.

From Slate Aug. 21, 2024

However, naltrexone, in both short- and long-acting forms, has the opposite pharmacology: it antagonizes mu receptors, occupying them without activating them.

From Scientific American Sep. 13, 2023

Doug antagonizes his commander, avoids his station chores and occasionally does his job of monitoring the cosmos around him for any sign of intelligent life.

From New York Times Apr. 7, 2020

Stoner’s implacable stand antagonizes Walker’s brilliant and charismatic thesis adviser, Hollis Lomax, whose “body is grotesquely misshapen” by a hump on his back.

From Washington Post Nov. 2, 2015

Nothing worries and antagonizes a female bear more than to have people between her and her brood.

From "A Walk in the Woods" by Bill Bryson

But Adeyemi describes suffering somatic pain and panic attacks, alleging she is still being antagonized behind the scenes.

From Salon Jul. 31, 2026

Some also contend the deal has unnecessarily antagonized China, Australia’s main trading partner.

From The Wall Street Journal Oct. 21, 2025

So, people who are sophisticated litigators often don’t do that because it so often fails, and all you’re left with is an angered and antagonized judge who you’ve just called biased.

From Slate Apr. 11, 2024

Instead, he says, the experiment merely shows that, when antagonized the snakes are likely to put up a more spirited defense.

From Science Magazine Apr. 3, 2024

Fyntan and Celine must have been alarmed by our misguided outpost in Kilanga, where we slept in their same house, antagonized their former friends, even turned their parrot out to nature’s maw.

From "The Poisonwood Bible" by Barbara Kingsolver

She needs to maintain her popular tough stance on China without overly antagonizing Japan’s No. 2 customer for exports.

From Barron's Feb. 10, 2026

In it, more realities of the killing are clarified: Good wasn’t antagonizing the agent, and she didn’t turn her wheels to try to hit him, but instead to drive away slowly.

From Slate Jan. 13, 2026

Zohran Mamdani, who just swept to victory in the New York City mayoral race, already faces his next big challenge: making the right hires without alienating loyalists or further antagonizing skeptics.

From The Wall Street Journal Nov. 8, 2025

At the heart of the case was the late Frank Carson, a veteran Modesto defense attorney with a pugilistic style who delighted in antagonizing police and prosecutors.

From Los Angeles Times Apr. 17, 2025

Terryl felt like her mother blamed her for antagonizing Danny, and making things worse.

From "A Deadly Wandering: A Mystery, a Landmark Investigation, and the Astonishing Science of Attention in the Digital Age" by Matt Richtel

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