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Synonyms

Big C

American  
Or big C

noun

Slang.
  1. cancer.


Etymology

Origin of Big C

First recorded in 1970–75

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Graham Rennie from Larne, is taking part in the relay race to fundraise for The Big C Foundation, set up in memory of his three-year-old son Callum.

From BBC • May 3, 2026

Last year, it was won by You, Me and the Big C, in which Dame Deborah James, Lauren Mahon and Rachael Bland focused on living with cancer.

From BBC • Sep. 28, 2023

Then I got to work with Laura Linney on "The Big C," and then Julia Louis-Dreyfus on "Veep."

From Salon • Apr. 28, 2023

The host of the BBC's You, Me and the Big C podcast was praised for her no-nonsense approach to talking about cancer, having shared her experiences of treatment and daily life since her diagnosis.

From BBC • Apr. 4, 2023

If it weren't for Big C, I'd be real healthy!

From Through these Eyes The courageous struggle to find meaning in a life stressed with cancer by Isaacson, Lauren Ann

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