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Synonyms

Big C

American  
Or big C

noun

Slang.
  1. cancer.


Etymology

Origin of Big C

First recorded in 1970–75


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Graham Rennie from Larne, is taking part in the relay race to fundraise for The Big C Foundation, set up in memory of his three-year-old son Callum.

From BBC ● May 3, 2026

The You, Me and the Big C podcaster, who also set up the Bowelbabe cancer research fund, died last year aged 40.

From BBC ● May 3, 2023

Then I got to work with Laura Linney on "The Big C," and then Julia Louis-Dreyfus on "Veep."

From Salon ● Apr. 28, 2023

The host of the BBC's You, Me and the Big C podcast was praised for her no-nonsense approach to talking about cancer, having shared her experiences of treatment and daily life since her diagnosis.

From BBC ● Apr. 4, 2023

If it weren't for Big C, I'd be real healthy!

From Through these Eyes The courageous struggle to find meaning in a life stressed with cancer by Lauren Ann Isaacson

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