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Synonyms

Big C

American  
Or big C

noun

Slang.
  1. cancer.


Etymology

Origin of Big C

First recorded in 1970–75

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Graham Rennie from Larne, is taking part in the relay race to fundraise for The Big C Foundation, set up in memory of his three-year-old son Callum.

From BBC May 3, 2026

"For the 'whatever the weather walk' I raised £550 for the Big C charity to help with treatments and things here and helping to get more stuff for kids that come here," she adds.

From BBC Aug. 6, 2024

The You, Me and the Big C podcaster, who also set up the Bowelbabe cancer research fund, died last year aged 40.

From BBC May 3, 2023

Then I got to work with Laura Linney on "The Big C," and then Julia Louis-Dreyfus on "Veep."

From Salon Apr. 28, 2023

Nov. 13, 1984… Sometimes I wonder if at least a good third of my life has been spent sick. . . whether from Big C or other junk!

From Through these Eyes The courageous struggle to find meaning in a life stressed with cancer by Lauren Ann Isaacson

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