[ sen-truh-meer ]
/ ˈsɛn trəˌmɪər /

noun Cell Biology.

a specialized structure on the chromosome, appearing during cell division as the constricted central region where the two chromatids are held together and form an X shape.

Origin of centromere

First recorded in 1920–25; centro- + -mere

Related forms

cen·tro·mer·ic [sen-truh-mer-ik, -meer-] /ˌsɛn trəˈmɛr ɪk, -ˈmɪər-/, adjective
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

British Dictionary definitions for centromere


/ (ˈsɛntrəˌmɪə) /


the dense nonstaining region of a chromosome that attaches it to the spindle during mitosis

Derived Forms

centromeric (ˌsɛntrəˈmɛrɪk, -ˈmɪərɪk), adjective
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medicine definitions for centromere


[ sĕntrə-mîr′ ]


The most condensed and constricted region of a chromosome to which the spindle fiber is attached during mitosis.kinetochore
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

Science definitions for centromere


[ sĕntrə-mîr′ ]

The region of the chromosome to which the spindle fiber is attached during cell division (both mitosis and meiosis). The centromere is the constricted point at which the two chromatids forming the chromosome are joined together. See more at meiosis mitosis.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.