• synonyms


noun Cell Biology.
  1. a specialized structure on the chromosome, appearing during cell division as the constricted central region where the two chromatids are held together and form an X shape.
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Origin of centromere

First recorded in 1920–25; centro- + -mere
Related formscen·tro·mer·ic [sen-truh-mer-ik, -meer-] /ˌsɛn trəˈmɛr ɪk, -ˈmɪər-/, adjective
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

British Dictionary definitions for centromere


  1. the dense nonstaining region of a chromosome that attaches it to the spindle during mitosis
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Derived Formscentromeric (ˌsɛntrəˈmɛrɪk, -ˈmɪərɪk), adjective
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

centromere in Medicine


  1. The most condensed and constricted region of a chromosome to which the spindle fiber is attached during mitosis.kinetochore
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

centromere in Science


  1. The region of the chromosome to which the spindle fiber is attached during cell division (both mitosis and meiosis). The centromere is the constricted point at which the two chromatids forming the chromosome are joined together. See more at meiosis mitosis.
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The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.