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cocaine

American  
[koh-keyn, koh-keyn] / koʊˈkeɪn, ˈkoʊ keɪn /

noun

Pharmacology.
  1. a bitter, crystalline alkaloid, C 17 H 21 NO 4 , obtained from coca leaves, used as a local anesthetic and also widely used as an illicit drug for its stimulant and euphorigenic properties.


cocaine British  
/ kəˈkeɪn /

noun

  1. an addictive narcotic drug derived from coca leaves or synthesized, used medicinally as a topical anaesthetic. Formula: C 17 H 21 NO 4

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

cocaine Scientific  
/ kō-kān /
  1. A colorless or white crystalline alkaloid extracted from coca leaves. Cocaine is sometimes used in medicine as a local anesthetic, especially for the eyes, nose, or throat. It is also widely used as an illicit drug for its euphoric and stimulating effects. Chemical formula: C 17 H 21 NO 4 .


cocaine Cultural  
  1. A drug derived from the leaves of a shrub in South America that has an intoxicating effect on the body and can result in dependency if frequently used. Cocaine is used medically as a local anesthetic.


Discover More

Cocaine use constitutes a major drug problem in the United States.

Etymology

Origin of cocaine

First recorded in 1870–75; coca + -ine 1

Vocabulary lists containing cocaine

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Noboa, a close ally of US President Donald Trump, previously said that Washington was among "regional allies" taking part in the operation against drug cartels, which use Ecuador's ports to smuggle cocaine to international markets.

From Barron's • Mar. 7, 2026

Colombian officials said Petro planned to focus on defending his record in deterring drug trafficking, even though cocaine production is rising in Colombia.

From Los Angeles Times • Feb. 3, 2026

Successive Colombian governments received about $14 billion in U.S. aid to fight cocaine trafficking and insurgencies in close coordination with Washington—a partnership unmatched in the region.

From The Wall Street Journal • Feb. 2, 2026

"With one law, we can protect Generation Alpha from being sucked into purgatory by the predatory algorithms described by the man who created the feature as behavioural cocaine," Wells said.

From BBC • Dec. 4, 2025

The waning of the crack cocaine epidemic in New York was clearly a factor, but then again, it had been in steady decline well before crime dipped.

From "The Tipping Point" by Malcolm Gladwell

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