disease

American  

[dih-zeez] / dɪˈziz /

noun

1. a disordered or incorrectly functioning organ, part, structure, or system of the body resulting from the effect of genetic or developmental errors, infection, poisons, nutritional deficiency or imbalance, toxicity, or unfavorable environmental factors; illness; sickness; ailment.

   Synonyms:

   malady, disorder, infirmity, indisposition, distemper, derangement, complaint, morbidity

   Antonyms:

   health

2. any abnormal condition in a plant that interferes with its vital physiological processes, caused by pathogenic microorganisms, parasites, unfavorable environmental, genetic, or nutritional factors, etc.

3. any harmful, depraved, or morbid condition, as of the mind or society.

   His fascination with executions is a disease.

4. decomposition of a material under special circumstances.

   tin disease.

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verb (used with object)

diseased, diseasing

1. to affect with disease; make ill.

   Antonyms:

   cure

disease British  

/ dɪˈziːz /

noun

1. any impairment of normal physiological function affecting all or part of an organism, esp a specific pathological change caused by infection, stress, etc, producing characteristic symptoms; illness or sickness in general

2. a corresponding condition in plants

3. any situation or condition likened to this

   the disease of materialism

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Other Word Forms

• diseasedly adverb
• diseasedness noun

Etymology

Origin of disease

First recorded in 1300–50; Middle English disese, from Anglo-French dese(a)se, disaise; dis- ¹ + ease

Example Sentences

Marketers also claim thymosin-alpha, one of the more studied peptides, can help with immune function, Lyme disease and COVID-19.

From Salon • Apr. 4, 2026

They can even detect tuberculosis, an infectious disease that commonly affects the lungs, far quicker than it would be found in a lab using conventional microscopy, Apopo has said.

From BBC • Apr. 4, 2026

The clinical trial followed 97 patients with mild-to-moderate Crohn's disease across the United States.

From Science Daily • Apr. 3, 2026

Excessive rainfall creating disease issues for beans limited the amount of cocoa coming out of West African ports.

From The Wall Street Journal • Apr. 3, 2026

Of particular interest to a brainy, idealistic youth such as Farmer, Virchow helped define the field of medical anthropology—the study of human health and disease and public health care systems.

From "Mountains Beyond Mountains" by Tracy Kidder and Michael French

Related Words

• Cancer
• bug
• condition
• contamination
• defect
• disorder
• epidemic
• fever
• flu
• illness
• infection
• inflammation
• malady
• plague
• sickness
• stroke
• syndrome
• virus