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Synonyms

disease

American  
[dih-zeez] / dɪˈziz /

noun

  • diseases
    plural
  1. An image of the word disease as defined by a disordered or incorrectly functioning organ, part, structure, or system of the body resulting from the effect of genetic or developmental errors, infection, poisons, nutritional deficiency or imbalance, toxicity, or unfavorable environmental factors; illness; sickness; ailment.

    a disordered or incorrectly functioning organ, part, structure, or system of the body resulting from the effect of genetic or developmental errors, infection, poisons, nutritional deficiency or imbalance, toxicity, or unfavorable environmental factors; illness; sickness; ailment.

    Synonyms:
    malady, disorder, infirmity, indisposition, distemper, derangement, complaint, morbidity
    Antonyms:
    health
  2. any abnormal condition in a plant that interferes with its vital physiological processes, caused by pathogenic microorganisms, parasites, unfavorable environmental, genetic, or nutritional factors, etc.

  3. any harmful, depraved, or morbid condition, as of the mind or society.

    His fascination with executions is a disease.

  4. decomposition of a material under special circumstances.

    tin disease.


verb (used with object)

diseased, diseasing
  1. to affect with disease; make ill.

    Antonyms:
    cure
disease British  
/ dɪˈziːz /

noun

  1. any impairment of normal physiological function affecting all or part of an organism, esp a specific pathological change caused by infection, stress, etc, producing characteristic symptoms; illness or sickness in general

  2. a corresponding condition in plants

  3. any situation or condition likened to this

    the disease of materialism

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Derived Forms

Inflected Forms

Nouns


Etymology

Origin of disease

First recorded in 1300–50; Middle English disese, from Anglo-French dese(a)se, disaise; dis- 1 + ease


Explanation

A disease is a health condition that has a specific set of symptoms and traits — such as malaria or heart disease. Disease is not always about the human body being sick. Plants and animals are often the victims of disease. People also use the word disease in a more figurative sense to illustrate just how bad or damaging a negative influence can be — like the disease of greed among capitalists or the disease of plagiarism among college students.

Keep Reading on Vocabulary.com

Vocabulary lists containing disease

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

The deadly disease has killed more than 15,000 people in Africa over the past 50 years.

From Barron's ● Oct. 17, 2026

Observing these physical changes could offer new insights into how the disease affects blood cells.

From Science Daily ● Oct. 17, 2026

Yet many questions remain about what exactly these infinitesimal flecks of synthetic polymers do to human health, and how they might cause disease.

From Los Angeles Times ● Oct. 17, 2026

Necropsies found chronic inflammatory disease in the gastrointestinal systems in Peekachu and Rain.

From BBC ● Oct. 17, 2026

Unlike illnesses such as tuberculosis or flu, it can be difficult to hide an advanced case of Hansen’s disease.

From "At Last She Stood" by Erin Entrada Kelly

She had been suffering from multiple diseases, according to the department.

From Los Angeles Times ● Oct. 15, 2026

This comes as artificial intelligence is enabling tests that can better detect diseases in early stages and predict risk factors.

From The Wall Street Journal ● Oct. 14, 2026

The achievement could eventually help researchers develop new approaches to treating diseases caused by malfunctioning mitochondria.

From Science Daily ● Oct. 13, 2026

Droughts, intensive downpours and diseases have created challenges for tea growers across the world as they deal with the impact of a warming planet.

From BBC ● Oct. 13, 2026

His mother died, but she didn’t have any diseases, and neither does he.

From "A Boy Called Bat" by Elana K. Arnold

A new class of medications—known as “protein degraders”—are showing promise in going after a certain kind of hard-to-target protein in diseased cells.

From The Wall Street Journal ● Oct. 15, 2026

The first starts with terror of the unknown and unseen but culminates in sheer pathos; the latter keeps the reader guessing: Is the creature real or merely the product of a diseased imagination?

From The Wall Street Journal ● Oct. 9, 2026

Researchers collected tissue from both diseased and non-diseased areas of the heart.

From Science Daily ● Sep. 11, 2026

"Farmers may unknowingly buy diseased plants. The trees may look healthy initially, but after five or seven years they can suddenly die, causing huge financial losses," he says.

From BBC ● Sep. 4, 2026

But there’s something wrong with this voice, something diseased at its core.

From "An Ember in the Ashes" by Sabaa Tahir

They provide for your wants, hearken to your complaints, nurture you in sickness, with a diseasing fondness, and so render you incapable.

From Charlemont; Or, the Pride of the Village. a Tale of Kentucky by William Gilmore Simms

In either case we have diabetes, the sugar irritating and diseasing the kidneys as it passes.”

From Alcohol: A Dangerous and Unnecessary Medicine, How and Why What Medical Writers Say by Martha Meir Allen

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