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  • drug
    drug
    noun
    a chemical substance used in the treatment, cure, prevention, or diagnosis of disease or used to otherwise enhance physical or mental well-being.
  • Drug
    Drug
    noun
    the cosmic principle of disorder and falsehood.
Synonyms

drug

1 American  
[druhg] / drʌg /

noun

drugs plural
  1. Pharmacology. a chemical substance used in the treatment, cure, prevention, or diagnosis of disease or used to otherwise enhance physical or mental well-being.

  2. (in federal law)

    1. any substance recognized in the official pharmacopoeia or formulary of the nation.

    2. any substance intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease in humans or other animals.

    3. any article, other than food, intended to affect the structure or any function of the body of humans or other animals.

    4. any substance intended for use as a component of such a drug, but not a device or a part of a device.

  3. a habit-forming medicinal or illicit substance, especially a narcotic.

  4. drugs,

    1. chemical substances prepared and sold as pharmaceutical items, either by prescription or over the counter.

    2. personal hygienic items sold in a drugstore, as toothpaste, mouthwash, etc.

  5. Obsolete. any ingredient used in chemistry, pharmacy, dyeing, or the like.


verb (used with object)

drugged, drugging
  1. to administer a medicinal drug to.

  2. to stupefy or poison with a drug.

  3. to mix (food or drink) with a drug, especially a stupefying, narcotic, or poisonous drug.

  4. to administer anything nauseous to.

verb phrase

  1. drug up to take a drug, especially an illegal drug: athletes who drug up in the off-season.

    kids hiding under the school bleachers to drug up;

    athletes who drug up in the off-season.

idioms

  1. drug on the market, a commodity that is overabundant or in excess of demand in the market. Also drug in the market.

drug 2 American  
[druhg] / drʌg /

verb

Nonstandard: Chiefly Midland and Southern U.S.
  1. a simple past tense and past participle of drag.


Drug 3 American  
[droog] / drʊg /

noun

Zoroastrianism.
  1. the cosmic principle of disorder and falsehood.


drug British  
/ drʌɡ /

noun

  1. any synthetic, semisynthetic, or natural chemical substance used in the treatment, prevention, or diagnosis of disease, or for other medical reasons

  2. a chemical substance, esp a narcotic, taken for the pleasant effects it produces

  3. a commodity available in excess of the demands of the market

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

verb

  1. to mix a drug with (food, drink, etc)

  2. to administer a drug to

  3. to stupefy or poison with or as if with a drug

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
drug Scientific  
/ drŭg /
  1. A chemical substance, especially one prescribed by a medical provider, that is used in the diagnosis, treatment, or prevention of a condition or disease. Drugs are prescribed for a limited amount of time, as for an acute infection, or on a regular basis for chronic disorders, such as hypertension.

  2. A chemical substance such as a narcotic or a hallucinogen that affects the central nervous system and is used recreationally for perceived desirable effects on personality, perception, or behavior. Many recreational drugs are used illicitly and can be addictive.


Other Word Forms

Derived Forms

Inflected Forms

Nouns

Etymology

Origin of drug1

First recorded in 1300–50; Middle English drogges (plural), from Middle French drogue, of obscure origin

Origin of Drug3

From the Avestan word drauga

Explanation

A drug is a medicine. Before you travel to India, your doctor may prescribe a drug to protect you from getting malaria. A substance that makes a change in your body is a drug. Most often, a drug is medicine prescribed by a doctor to protect a patient from illness, cure them, or relieve their pain. Drug also means an illegal substance taken simply for the way it makes the user feel. Drug is also a verb that describes both taking illegal drugs and giving someone a drug secretly, such as slipping it into their food or drink.

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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Since returning to office in 2025, US President Donald Trump has intensified efforts against Latin American drug cartels and their operations.

From BBC Jul. 28, 2026

The Centers for Medicare and Medicaid Services has said it started the program in 2025 to hold drug prices steady.

From MarketWatch Jul. 28, 2026

The pharmaceutical industry, meanwhile, was eager to create “the next blockbuster drug, something on the order of Thorazine and Valium.”

From The Wall Street Journal Jul. 28, 2026

Medicare is scrapping a temporary program that helped keep the price of monthly premiums in check for older adults with Part D prescription drug plans.

From MarketWatch Jul. 28, 2026

No more being stuck inside whitewashed buildings all over the world as doctors try drug after drug, treatment after treatment, none of them working.

From "Five Feet Apart" by Rachael Lippincott

The panel recommendations are not binding, but the Food and Drug Administration historically has given them significant weight.

From Barron's Jul. 24, 2026

A group of experts advising the Food and Drug Administration voted “no” for the first time on reclassifying a peptide, citing safety and efficacy unknowns.

From MarketWatch Jul. 24, 2026

The Food and Drug Administration last week said it traced the bug to Taco Bell iceberg lettuce.

From The Wall Street Journal Jul. 22, 2026

The case came to light after officials from the Ministry of Food and Drug Safety found reviews that diners had posted online with photographs of dishes sprinkled with ants.

From BBC Jul. 22, 2026

If the farmer scrupulously follows the instructions on the labels, his use of agricultural chemicals will produce no residues larger than are permitted by the Food and Drug Administration.

From "Silent Spring" by Rachel Carson

American policymakers should concentrate their efforts on accelerating the domestic AI industry and eliminating bottlenecks that would slow down AI-bred innovations such as new drugs, he said.

From The Wall Street Journal Jul. 29, 2026

In the past 10 years the drugs have increasingly been made available to more cancer patients in Northern Ireland.

From BBC Jul. 28, 2026

It is also a powerful reminder of the ordeal of serious mental illness and the ever-pressing need to find better drugs to treat it.

From The Wall Street Journal Jul. 28, 2026

Almost half of all children living with HIV were not receiving these drugs last year, the report warned.

From Barron's Jul. 27, 2026

Politely he asks if there is a way that he can pay for his care, as well as the antibiotics and the anti-inflammatory drugs.

From "Enrique's Journey" by Sonia Nazario

Had Raynella drugged him and staged an accident?

From The Wall Street Journal May 1, 2026

"He arrived with brain trauma, sedated, drugged, breathing with a ventilator," Interior Minister Armando Benedetti said.

From Barron's Oct. 19, 2025

Mr. Olson was working at Fort Detrick and was unwittingly drugged with LSD in a CIA mind-control experiment that ended with him falling to his death from a New York hotel window.

From Washington Times Dec. 6, 2023

Death for the terminally ill can often be cruel and slow, physicians told the BBC, with the patient's final days spent slipping in and out of a drugged consciousness.

From BBC Jan. 13, 2023

My mind felt slow, drugged with the strain of thought.

From "The Darkest Minds" by Alexandra Bracken

With her brown bobbed haircut and round sunglasses, Pelicot has become an international feminist symbol, inspiring a change to French rape laws and a public reckoning with the problem of drugging women.

From Barron's Feb. 11, 2026

If there is widespread dog drugging, I certainly didn’t find that or hear about it, and I asked some questions along those lines.

From Salon Apr. 23, 2024

This new information could prove to be especially useful to drug developers hoping to create a new cancer treatment by drugging this interaction.

From Science Daily Nov. 15, 2023

About half the complaints that California Advocates for Nursing Home Reform receives about inappropriate drugging of residents involve Depakote, said Anthony Chicotel, the group’s top lawyer.

From New York Times Sep. 11, 2021

And finally he had great faith in the water, as you have already seen; whereas he had lost all faith in drugging and dosing.

From Forty Years in the Wilderness of Pills and Powders Cogitations and Confessions of an Aged Physician by Alcott, William A. (William Andrus)

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