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hematopoiesis

American  
[hi-mat-oh-poi-ee-sis, hee-muh-toh-, hem-uh-] / hɪˌmæt oʊ pɔɪˈi sɪs, ˌhi mə toʊ-, ˌhɛm ə- /

noun

  1. the formation of blood.


Usage

What is hematopoiesis? Hematopoiesis is the formation of blood. Human blood cells are highly specialized, meaning they are formed to do specific jobs. Yet all blood cells come from the same place. Most of hematopoiesis begins in the bone marrow and blood-creating organs like the liver, where stem cells commit themselves to becoming a certain type of blood cell and are then transitioned into the bloodstream. Hematopoiesis begins when a stem cell receives a signal that a certain type of blood cell is needed. The cell will transition into a precursor cell for either red or white blood cells. Then the cells will begin moving through the body. Eventually, the cell will fully transition into a certain type of red or white cells, such as a granulocyte, erythrocyte, leukocyte, monocyte, or lymphocyte. Some of the matter and cytoplasm that the stem cells shed during their transition becomes blood platelets. Example: When your body begins losing blood, your kidneys send a signal to your cells to accelerate the hematopoiesis process for red blood cells.

Other Word Forms

Etymology

Origin of hematopoiesis

From the New Latin word haematopoiēsis, dating back to 1850–55; see hemato-, -poiesis

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Aging HSCs are also linked to clonal hematopoiesis, an asymptomatic condition considered a premalignant state that raises the risk of blood cancers and inflammatory diseases.

From Science Daily • May 12, 2026

Consider clonal hematopoiesis of indeterminate potential, or CHIP, in which blood cells harbor mutations often seen in blood cancer, giving them a growth advantage over their well-behaved neighbors.

From The Wall Street Journal • Apr. 20, 2026

Clonal hematopoiesis, a variety of mosaicism that affects blood-forming cells and becomes more common with age, almost doubles the likelihood of developing cardiovascular disease and boosts the risk of dying from any cause by 40%.

From Science Magazine • Aug. 15, 2023

Clonal hematopoiesis is not cancer—people with the condition have a normal number of blood cells—but it can be a prelude to blood cancers such as leukemia and lymphoma.

From Science Magazine • Dec. 13, 2021

Figure 3.34 Hematopoiesis The process of hematopoiesis involves the differentiation of multipotent cells into blood and immune cells.

From Textbooks • Jun. 19, 2013

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