iproniazid

[ahy-pruh-nahy-uh-zid]

noun

Pharmacology.

1. a compound, C 9 H 13 N 3 O, used in the treatment of mental depression and tuberculosis.

Word History and Origins

Origin of iproniazid¹

First recorded in 1950–55; i(so)pro(pyl) + ni(cotine) + az- + -id ⁴

Example Sentences

One drug, iproniazid, was being used to treat tuberculosis when doctors realized that it helped improve patients’ mood.

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His 1967 paper, titled “The Biochemistry of Affective Disorders,” reviewed studies of reserpine, iproniazid, and other recently discovered drugs, and proposed that low levels of a different neurotransmitter, serotonin, could underlie depressive illness.

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That long and winding road began with the antibiotic iproniazid.

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Iproniazid transformed the treatment of tuberculosis in the 1950s.

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The first, called iproniazid, was found by accident when it was being tested as a treatment for tuberculosis.

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