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Synonyms

mainline

American  
[meyn-lahyn, -lahyn] / ˈmeɪnˌlaɪn, -ˈlaɪn /

verb (used without object)

Slang.
mainlines, present (3rd person singular) mainlined, past participle, past mainlining present participle
  1. to inject a narcotic, especially heroin, directly into a vein.

  2. to use or enjoy something without restriction.

    to mainline on TV movies.


verb (used with object)

Slang.
mainlines, present (3rd person singular) mainlined, past participle, past mainlining present participle
  1. to inject (a narcotic, especially heroin) directly into a vein.

  2. to use, enjoy, or imbibe (something) without restriction.

    mainlining coffee all day long.

adjective

  1. having a principal, established, or widely accepted position; major; mainstream.

    the membership of mainline churches.

Other Word Forms

Etymology

Origin of mainline

1935–40, v., adj. use of main line

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Is there any scope to speed up the delivery of new stations along the south Wales mainline, the first of which aren't projected to get underway until 2029?

From BBC • May 29, 2026

In the aftermath of the 2008 financial crisis, Maybach was reorganized as Mercedes-Maybach—a sub-brand building small numbers of technically evolved, superluxury variants of mainline products.

From The Wall Street Journal • May 2, 2026

It could have come to life as a lesser kind of Ferrari, a diminished derivative of one of the company’s mainline GT cars, with a turbocharged V8 under the hood.

From The Wall Street Journal • Apr. 18, 2026

It is the main station for all services on the west coast mainline to England and also operates services throughout central Scotland.

From BBC • Mar. 10, 2026

Of a student body of 5,700, about 400 participate in one of three evangelical student groups—more than the number of active mainline Protestants, the campus chaplain says.

From "Class Matters" by The New York Times

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