- Also called break . a sudden departure from the parent type in one or more heritable characteristics, caused by a change in a gene or a chromosome.
- Also called sport . an individual, species, or the like, resulting from such a departure.
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How to use mutation in a sentence
That’s because it’s prone to introducing unexpected mutations that are hard to spot, and it can generate embryos with a mixture of edited and unedited cells.The “staged rollout” of gene-modified babies could start with sickle-cell disease|Amy Nordrum|September 3, 2020|MIT Technology Review
Gene editing might be an option when 25 percent or fewer of a couple’s embryos would be free of the disease-causing mutation.Strict new guidelines lay out a path to heritable human gene editing|Tina Hesman Saey|September 3, 2020|Science News
When geneticists need to understand what genes do, they can create laboratory mice with “knockout” mutations and see whether and how the animals cope with the loss.By Losing Genes, Life Often Evolved More Complexity|Viviane Callier|September 1, 2020|Quanta Magazine
Dowling’s theory predicts that the faster the mitochondrial mutation rate is, the more often the members of that species will need to have sex.
Without sex we’d have a situation where mitochondrial mutations accumulate much faster and the nucleus could not come up quickly enough with co-adapted mutations.
This is the actual Calaveras Fault, forcing its way through town, bringing architectural mutation along with it.
Those with the disease have some cells that are genetically normal and some with the mutation.
For some illnesses, having a mutation in one specific gene usually—but not always—caused disease.
If scientists identify 100 individuals with the same mutation, and 75 of them have disease, the penetrance is 75 percent.
This was a mutation of a relationship that should, in theory, be unbreakably strong.Their Cordial Meeting Proves the Common Bonds of Obama and Pope Francis|Joshua DuBois|March 27, 2014|DAILY BEAST
Nor is it difficult to discover some of the circumstances that tended to bring about this radical mutation of policy.History of the Rise of the Huguenots|Henry Baird
Do species change by the gradual elimination of the unfit, or do they change by sudden leaps, the "mutation" theory of de Vries?
There is no trace of such vocalic mutation (“umlaut”) in Gothic, our most archaic Germanic language.Language|Edward Sapir
Still more remarkable is the mutation and addition of new words of especially definite meaning among certain classes.
Such differentiations in tone our own people make also, and the mutation of meaning is very close.
British Dictionary definitions for mutation
- (in Germanic languages) another name for umlaut
- (in Celtic languages) a phonetic change in certain initial consonants caused by a preceding word