nodule

American  

[noj-ool] / ˈnɒdʒ ul /

noun

• nodules
  plural

1. a small node, knot, or knob.

2. a small, rounded mass or lump.

3. Botany. a tubercle.

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nodule British  

/ ˈnɒdjuːl /

noun

1. a small knot, lump, or node

2. Also called: root nodule.  any of the knoblike outgrowths on the roots of clover and many other legumes: contain bacteria involved in nitrogen fixation

3. anatomy any small node or knoblike protuberance

4. a small rounded lump of rock or mineral substance, esp in a matrix of different rock material

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nodule Scientific  

/ nŏj′o̅o̅l /

1. A small, usually hard mass of tissue in the body.

2. A small, knoblike outgrowth found on the roots of many legumes, such as alfalfa, beans, and peas. Nodules grow after the roots have been infected with nitrogen-fixing bacteria of the genus Rhizobium.

3. See more at legume

4. A small, rounded lump of a mineral or mixture of minerals that is distinct from and usually harder than the surrounding rock or sediment. Nodules often form by replacement of a small part of the rocks in which they form.

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Other Word Forms

Derived Forms

• nodular
  adjective

Inflected Forms

Nouns

• nodules
  plural

Etymology

Origin of nodule

1590–1600; < Latin nōdulus a little knot, equivalent to nōd ( us ) node + -ulus -ule

Explanation

A nodule is a small, raised bump under the skin. You might notice a nodule on the top of your foot after spraining your ankle. Any solid bump or node that you can feel just beneath your skin is a nodule. You may have noticed nodules in your neck when you have a sore throat or a nodule on your shin where you bumped it into the coffee table. Another kind of nodule is very similar, but appears on a plant's surface. The Latin root word is nodulus, "small knot," from nodus, or "knot."

Example Sentences

See Examples For:

nodule nodules

The same AI pattern-recognition that’s learning to spot breast tumors is being applied to thyroid screening, lung nodule detection and colonoscopies.

From The Wall Street Journal ● May 4, 2026

The diagnosis occurred last week, following a urinary screening that revealed a small nodule in his prostate, which revealed the aggressive Stage 4 prostate cancer, according to the statement.

From Slate ● May 20, 2025

A small nodule has been found in the prostate of former President Joe Biden during a routine physical exam.

From Los Angeles Times ● May 18, 2025

It is what scientists call a polymetallic nodule, created over millennia as minerals accumulate on the seabed.

From BBC ● Dec. 9, 2024

“Right,” he said, and gripped a golden nodule that protruded from the trunk.

From "Impossible Creatures" by Katherine Rundell

Tyler suffered nodules on her vocal cords and underwent surgery to remove them.

From Los Angeles Times ● Jul. 9, 2026

"It was her leg which was stuck within a rock cleft, and there was some space around the side of it and also nodules of rock which were stopping it from coming out," Rees said.

From BBC ● Jun. 27, 2026

"Maybe the ridges were cemented by minerals first, and later episodes of groundwater left nodules around them."

From Science Daily ● Mar. 14, 2026

Some researchers have suggested that the oxygen was not coming from the nodules, but instead were just air bubbles trapped in the measuring instruments.

From Barron's ● Jan. 20, 2026

Two singed pink nodules drop into a glass of fluid.

From "The Last Cuentista" by Donna Barba Higuera

Related Words

• growth
• knot
• node