nodule
Americannoun
-
a small node, knot, or knob.
-
a small, rounded mass or lump.
-
Botany. a tubercle.
noun
-
a small knot, lump, or node
-
Also called: root nodule. any of the knoblike outgrowths on the roots of clover and many other legumes: contain bacteria involved in nitrogen fixation
-
anatomy any small node or knoblike protuberance
-
a small rounded lump of rock or mineral substance, esp in a matrix of different rock material
-
A small, usually hard mass of tissue in the body.
-
A small, knoblike outgrowth found on the roots of many legumes, such as alfalfa, beans, and peas. Nodules grow after the roots have been infected with nitrogen-fixing bacteria of the genus Rhizobium.
-
See more at legume
-
A small, rounded lump of a mineral or mixture of minerals that is distinct from and usually harder than the surrounding rock or sediment. Nodules often form by replacement of a small part of the rocks in which they form.
Other Word Forms
- nodular adjective
Etymology
Origin of nodule
1590–1600; < Latin nōdulus a little knot, equivalent to nōd ( us ) node + -ulus -ule
Explanation
A nodule is a small, raised bump under the skin. You might notice a nodule on the top of your foot after spraining your ankle. Any solid bump or node that you can feel just beneath your skin is a nodule. You may have noticed nodules in your neck when you have a sore throat or a nodule on your shin where you bumped it into the coffee table. Another kind of nodule is very similar, but appears on a plant's surface. The Latin root word is nodulus, "small knot," from nodus, or "knot."
Vocabulary lists containing nodule
The Immortal Life of Henrietta Lacks
Looking to grow your vocabulary? Check out this interactive, curated word list from our team of English language specialists at Vocabulary.com – one of over 17,000 lists we've built to help learners worldwide!
National Nurses Week: Medical Branches and Conditions
Interested in learning more words like this one? Our team at Vocabulary.com has got you covered! You can review flashcards, quiz yourself, practice spelling, and more – and it's all completely free to use!
The Lives of a Cell
Want to remember this word for good? Start your learning journey today with our library of interactive, themed word lists built by the experts at Vocabulary.com – we'll help you make the most of your study time!
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
Another limitation is having an incidental finding, such as a lung nodule.
From The Wall Street Journal • Mar. 30, 2026
The leftover sediment and fine nodule fragments are then released back into the ocean.
From Science Daily • Nov. 8, 2025
The discovery was made after the Democrat politician reported urinary symptoms which led doctors to find a small nodule on his prostate.
From BBC • Oct. 11, 2025
The diagnosis occurred last week, following a urinary screening that revealed a small nodule in his prostate, which revealed the aggressive Stage 4 prostate cancer, according to the statement.
From Slate • May 20, 2025
“Right,” he said, and gripped a golden nodule that protruded from the trunk.
From "Impossible Creatures" by Katherine Rundell
![]()
Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.