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protease inhibitor

American  

noun

Pharmacology.
  1. a drug that inhibits the action of protease, especially any of a class of antiviral drugs that prevent the cleavage and replication of HIV proteins.


protease inhibitor British  

noun

  1. any one of a class of antiviral drugs that impair the growth and replication of HIV by inhibiting the action of protease produced by the virus: used in the treatment of AIDS

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of protease inhibitor

First recorded in 1935–40

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Their report, which will appear in Science, shows that an alternative medication, a viral papain-like protease inhibitor, inhibits disease progression in animals, a necessary step before human drug trials.

From Science Daily

And over a few years, we developed a series of antiretroviral drugs, then we added the protease inhibitor.

From Los Angeles Times

While drugs that initially seemed promising fell short, by the mid-90s, protease inhibitors slashed virus levels and delivered a medical miracle.

From New York Times

It was just after the data on these protease inhibitors had been unveiled at a major scientific conference.

From New York Times

Paxlovid, known as a protease inhibitor, is designed to block an enzyme the virus needs in order to multiply.

From BBC