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pyrogen

[ pahy-ruh-juhn, -jen ]

noun

  1. a substance, as a thermostable bacterial toxin, that produces a rise in temperature in a human or animal.


pyrogen

/ ˈpaɪrəʊˌdʒɛn /

noun

  1. any of a group of substances that cause a rise in temperature in an animal body
“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012


pyrogen

/ rə-jən /

  1. A polypeptide that produces fever by causing metabolic changes in the hypothalamus. Pyrogens are either exogenous (produced by infectious agents) or endogenous (produced by cells in the body such as macrophages).


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Word History and Origins

Origin of pyrogen1

First recorded in 1855–60; pyro- + -gen
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Example Sentences

Pyrogenet′ic, Pyrog′enous, producing fire: produced by fire; Pyrogen′ic, producing fever.

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pyrogallolpyrogenic