[ pahy-ruh-juhn, -jen ]

  1. a substance, as a thermostable bacterial toxin, that produces a rise in temperature in a human or animal.

Origin of pyrogen

First recorded in 1855–60; pyro- + -gen

Words Nearby pyrogen Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2024

How to use pyrogen in a sentence

British Dictionary definitions for pyrogen


/ (ˈpaɪrəʊˌdʒɛn) /

  1. any of a group of substances that cause a rise in temperature in an animal body

Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Scientific definitions for pyrogen


[ rə-jən ]

  1. A polypeptide that produces fever by causing metabolic changes in the hypothalamus. Pyrogens are either exogenous (produced by infectious agents) or endogenous (produced by cells in the body such as macrophages).

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