[pahy-ruh-juh n, -jen]
- a substance, as a thermostable bacterial toxin, that produces a rise in temperature in a human or animal.
Origin of pyrogen
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
Examples from the Web for pyrogen
Pyrogenet′ic, Pyrog′enous, producing fire: produced by fire; Pyrogen′ic, producing fever.
- any of a group of substances that cause a rise in temperature in an animal body
Word Origin and History for pyrogen
Online Etymology Dictionary, © 2010 Douglas Harper
- A substance that produces a fever.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
- A polypeptide that produces fever by causing metabolic changes in the hypothalamus. Pyrogens are either exogenous (produced by infectious agents) or endogenous (produced by cells in the body such as macrophages).
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.