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recombination

American  
[ree-kom-buh-ney-shuhn] / ˌri kɒm bəˈneɪ ʃən /
Genetics.
  1. the formation of new combinations of genes, either naturally, by crossing over or independent assortment, or in the laboratory by direct manipulation of genetic material.


recombination British  
/ ˌriːkɒmbɪˈneɪʃən /

noun

  1. genetics any of several processes by which genetic material of different origins becomes combined. It most commonly occurs between two sets of parental chromosomes during production of germ cells

  2. physics the union of free electrons and holes in a semiconductor or of free ions and electrons in a plasma

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of recombination

1820–30, for general sense; 1900–05 for current sense; re- + combination

Explanation

In genetics, recombination is the process of two organisms exchanging pieces of genetic material. It's through recombination that two brown-eyed parents can end up with a blue-eyed baby. Recombination is responsible for genetic diversity — in other words, for offspring that aren't just like their parents. It happens at various stages of reproduction, notably during meiosis when chromosomes swap segments of DNA. This science term comes up in chemistry and physics as well, when molecules bond together or ions and electrons are joined. Recombination, "be united again," comes from the Late Latin combinationem, "a joining together two by two."

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Vocabulary lists containing recombination

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

It's not just the resurgence of ancient diseases, but the fact that pathogens can and will trade genetic information if they come into contact with one another, a process known as viral recombination.

From Salon • Apr. 24, 2025

Natural selection leaves subtle signatures on our genome, but these marks can erode over generations due to recombination, where segments of DNA are shuffled and diluted.

From Science Daily • Nov. 19, 2024

XEC is a recombination of two different, little-discussed subvariants: KS.1.1 and KP.3.3,

From Los Angeles Times • Aug. 30, 2024

Moreover, fabricating tandem organic solar cells of these types are challenging because they need a robust interconnection layer capable of facilitating efficient charge recombination while maintaining high transparency.

From Science Daily • Apr. 8, 2024

And during the recombination of DNA, the strategy of interposing base against base is deployed yet again to restore damaged DNA.

From "The Gene" by Siddhartha Mukherjee

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