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Synonyms

mainline

American  
[meyn-lahyn, -lahyn] / ˈmeɪnˌlaɪn, -ˈlaɪn /

verb (used without object)

Slang.
mainlines, present (3rd person singular) mainlined, past participle, past mainlining present participle
  1. to inject a narcotic, especially heroin, directly into a vein.

  2. to use or enjoy something without restriction.

    to mainline on TV movies.


verb (used with object)

Slang.
mainlines, present (3rd person singular) mainlined, past participle, past mainlining present participle
  1. to inject (a narcotic, especially heroin) directly into a vein.

  2. to use, enjoy, or imbibe (something) without restriction.

    mainlining coffee all day long.

adjective

  1. having a principal, established, or widely accepted position; major; mainstream.

    the membership of mainline churches.

Other Word Forms

Inflected Forms

Participles

Conjugated Forms

Present

Past

Future

Etymology

Origin of mainline

1935–40, v., adj. use of main line

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Located above a busy mainline railway station, MSG is slap bang in the beating heart of tourist and commercial Manhattan.

From Barron's Jul. 1, 2026

Technology will be rolled out across 1,400 trains on mainline nationalised services allowing them to connect to low-earth satellites, instead of mobile networks.

From BBC May 30, 2026

“We’ve made it kind of core to who Allegiant is to seek out opportunities that aren’t typically served by mainline carriers,” said Drew Wells, the airline’s chief commercial officer.

From The Wall Street Journal May 17, 2026

In 2026, the railway is used by regular passenger services, commuters, steam engines and even mainline trains travelling between London and Glasgow when a diversion is required.

From BBC May 1, 2026

But over the last forty years, evangelicals have pulled steadily closer in income and education to mainline Protestants in the historically affluent establishment denominations.

From "Class Matters" by The New York Times

He mainlines all of his romantic entanglements as if they were the antidote to his unresolved traumas.

From Salon Apr. 25, 2025

Afterward, Healey said the agency was underestimating the blockages on Westlake, including relocation of two sewer mainlines.

From Seattle Times Jul. 28, 2023

Current labor agreements ensure that freight trains on mainlines have two people — an engineer and conductor — onboard.

From Washington Post Mar. 3, 2023

Other operators will also run some trains on the east coast and west coast mainlines.

From BBC Jun. 15, 2022

Send this to someone who has a lot on her plate and needs this simple reminder as she mainlines caffeine.

From Slate Apr. 27, 2021

Johnson said that businesses had mainlined on low-wage imported labour for nearly 25 years and that they should now pay their workers more and invest more.

From Reuters Oct. 5, 2021

And most likely from doc-chockablock behemoth Netflix, whose mainlined hits “Frye: The Greatest Party That Never Happened” and “Tiger King” have inspired a term for reveling in the story of a scam unraveled: schaden-fraud.

From Los Angeles Times Mar. 11, 2021

In 10 weeks as an editing intern, I mainlined more plays, musicals, ballets and cabaret performances than many people see in their entire lives.

From New York Times Aug. 28, 2019

I mean, they’re really being mainlined right into your brain.

From Washington Post Oct. 15, 2018

It is less a video game than mainlined anxiety, its jump-scares timed with sadistic precision and its long, shadow-splashed corridors masterpieces of unnerving light design.

From Slate Feb. 1, 2011

The ubiquity of holiday songs also represents a rare monocultural music moment—even though listeners are spread across multiple streaming services and social-media platforms, many of them are mainlining the same tunes.

From The Wall Street Journal Dec. 14, 2025

In some ways, I feel like a conspiracy junkie who has relapsed, mainlining paranoia and dread.

From Salon Jul. 17, 2024

He was mainlining applause from the public gallery.

From Washington Post Jul. 8, 2022

VERDICT: Watching the 2021 Jets is like mainlining tryptophan.

From New York Times Nov. 21, 2021

Youths, I am told, speak of “hopium” and “copium,” but we need a word that incorporates the never-ending mainlining of information as well as the positive or negative cast of that information.

From Slate Nov. 6, 2020

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