translocation

American  

[trans-loh-key-shuhn, tranz-] / ˌtræns loʊˈkeɪ ʃən, ˌtrænz- /

noun

1. a change of location.

2. Genetics. a chromosomal rearrangement in which a segment of genetic material from one chromosome becomes heritably linked to another chromosome.

3. Botany. the conduction of soluble food material from one part of a plant to another.

---

translocation British  

/ ˌtrænzləʊˈkeɪʃən /

noun

1. genetics the transfer of one part of a chromosome to another part of the same or a different chromosome, resulting in rearrangement of the genes

2. botany the transport of minerals, sugars, etc, in solution within a plant

3. a movement from one position or place to another

---

translocation Scientific  

/ trăns′lō-kā′shən /

1. A chromosomal aberration in which a chromosomal segment changes position, usually moving from one chromosome to a different, nonhomologous chromosome. In one type of Down Syndrome, for example, translocation of a large segment of chromosome 21 to another chromosome results in an individual who has the genetic equivalent of three chromosomes 21 and thus has the phenotype of Down syndrome but who has a normal total number of chromosomes. A translocation within a given chromosome is called a shift.

---

Other Word Forms

• nontranslocation noun

Etymology

Origin of translocation

First recorded in 1615–25; trans- + location

Example Sentences

The England Species Reintroductions Taskforce, an independent advisory group, guides conservation and species translocation efforts.

From BBC

“In the past this may have been to supplement stocks, plant fish or plan around water diversions or dams,” he said, “but in the modern era, rescues and translocations are used as management tools.”

From Los Angeles Times

She is also working on a progress report of current translocations.

From Los Angeles Times

The study revealed that a translocation between chromosome 7 and 12 was already present in some haematopoietic stem cells in the umbilical cord.

From Science Daily

Both Korbel and Sanders, Group Leader at the Max Delbrück Center study how genetic structural variation -- deletions, duplications, inversions, and translocations of large sections of the human genome -- contributes to the development of disease.

From Science Daily

Related Words

• about-face
• alteration
• change
• conversion
• deviation
• move
• transfer
• transformation
• variation