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illness

American  
[il-nis] / ˈɪl nɪs /

noun

illnesses plural
  1. poor health; sickness.

    He grew up in an environment known for poverty, illness, and little opportunity for education.

  2. a specific sickness or disease, or an instance of such.

    Please be as accurate as possible in listing your childhood illnesses.

    Synonyms:
    infirmity, affliction, ailment
  3. Obsolete. wickedness.


illness British  
/ ˈɪlnɪs /

noun

  1. a disease or indisposition; sickness

  2. a state of ill health

  3. obsolete wickedness

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Usage

What does illness mean? Illness is a state of poor health or sickness, as in I’ve had to miss a lot of work due to illness. The word illness is also commonly used to refer to a disease or instance of sickness. This sense of the word is often used when the type of disease is uncertain or unknown or when someone doesn’t want to specify what it is, as in They said that he is in the hospital with an illness, but they didn’t provide any further details. The word illness is based on the adjective ill, meaning sick. Example: The best way to avoid illness is to thoroughly wash your hands.

Other Word Forms

Noun Inflected Forms

Etymology

Origin of illness

First recorded in 1490–1500; ill + -ness

Compare meaning

How does illness compare to similar and commonly confused words? Explore the most common comparisons:

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Then you can truly enjoy your actual days off and better avoid burnout, something 53% of workers report experiencing, according to a 2026 survey by the National Alliance on Mental Illness.

From MarketWatch • Jun. 30, 2026

EastEnders' writers sought advice from mental health charities Samaritans, Mind and Rethink Mental Illness.

From BBC • May 1, 2026

Illness comes whether you are poor or rich, whether you are good or bad.

From Los Angeles Times • Mar. 4, 2026

Illness is predicted to spread faster, infect more people and put higher-risk groups at greater chance of being seriously ill or hospitalized.

From Salon • Nov. 28, 2025

Illness and death still exist and cannot be hidden.

From "The Lives of a Cell" by Lewis Thomas

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