genome
Americannoun
noun
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the full complement of genetic material within an organism
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all the genes comprising a haploid set of chromosomes
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The total amount of genetic information in the chromosomes of an organism, including its genes and DNA sequences. The genome of eukaryotes is made up of a single, haploid set of chromosomes that is contained in the nucleus of every cell and exists in two copies in all cells except reproductive and red blood cells. The human genome is made up of about 20,000 to 25,000 genes.
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Compare proteome
Other Word Forms
Derived Forms
Inflected Forms
Nouns
Etymology
Origin of genome
First recorded in 1925–30; from German Genom, from Gen gene + (Chromos)om chromosome
Explanation
The human genome is the map of your DNA, the double helix that contains all your genes. Your genome is all the genetic material contained in your 23 pairs of chromosomes, a total of more than 20,000 genes. Every organism has its own unique genome. "The Human Genome Project," completed in 2003, was an international effort to identify all the genes in human DNA and to determine the sequences of the 3 billion (yes, billion) base pairs — the smaller units that make up DNA. It took 13 years. Genome research has helped diagnose disease and find genetic markers for certain diseases.
Vocabulary lists containing genome
This Week In Words: March 29–April 4, 2020
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Genetics - Middle School
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Life Science: Genetics and Evolution
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Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
See Examples For:
To better understand the disease, the researchers used whole genome sequencing to compare tumor samples with healthy tissue from the same geckos.
From Science Daily ● Jul. 15, 2026
Department of Energy jointly announced that they had completed the sequencing of the human genome, which could ultimately unlock the mysteries of human health.
From The Wall Street Journal ● Jun. 26, 2026
Traditional approaches often depend on comparing a polyploid genome with known diploid ancestors.
From Science Daily ● Jun. 19, 2026
According to the analysis, some contributors to the strawberry genome may have been extinct or remain unsampled, underscoring the complexity of polyploid genome evolution.
From Science Daily ● Jun. 19, 2026
They conduct the genome, thereby playing out its music—activating the viola at the fourteenth minute, a crash of cymbals during the arpeggio, a roll of drums at the crescendo.
From "The Gene" by Siddhartha Mukherjee
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Together with local leopard experts and evolutionary biologists, we collected muscle or skin tissue of the leopards and compared them with genomes of leopards from other parts of Africa.
From Science Daily ● Jun. 24, 2026
The framework follows genome evolution across three broad stages: before ancestral species diverged, during their separate evolutionary histories, and after their genomes merged.
From Science Daily ● Jun. 19, 2026
"This work demonstrates how transposable elements can function as evolutionary time stamps embedded in plant genomes," said one of the study's senior authors.
From Science Daily ● Jun. 19, 2026
The team developed a bioinformatic framework capable of reconstructing the evolutionary history of complex polyploid genomes.
From Science Daily ● Jun. 19, 2026
Cytoplasm will flow easily from one to the other, the nuclei will combine, and it will become, for a time anyway, a single cell with two complete, alien genomes, ready to dance, ready to multiply.
From "The Lives of a Cell" by Lewis Thomas
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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.