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Synonyms

mainline

American  
[meyn-lahyn, -lahyn] / ˈmeɪnˌlaɪn, -ˈlaɪn /

verb (used without object)

Slang.
  • mainlines,
    present (3rd person singular)
  • mainlined,
    past participle,  past
  • mainlining
    present participle
  1. to inject a narcotic, especially heroin, directly into a vein.

  2. to use or enjoy something without restriction.

    to mainline on TV movies.


verb (used with object)

Slang.
  • mainlines,
    present (3rd person singular)
  • mainlined,
    past participle,  past
  • mainlining
    present participle
  1. to inject (a narcotic, especially heroin) directly into a vein.

  2. to use, enjoy, or imbibe (something) without restriction.

    mainlining coffee all day long.

adjective

  1. having a principal, established, or widely accepted position; major; mainstream.

    the membership of mainline churches.

Other Word Forms

Inflected Forms

Participles

Conjugated Forms

Present

Past

Future

Etymology

Origin of mainline

1935–40, v., adj. use of main line

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

DWP plans to replace about 45 miles of mainline, which deliver water to individual services across neighborhoods, this fiscal year.

From Los Angeles Times Jul. 25, 2026

Located above a busy mainline railway station, MSG is slap bang in the beating heart of tourist and commercial Manhattan.

From Barron's Jul. 1, 2026

The game will launch on current-generation consoles, PC and Nintendo Switch 2, marking the first mainline Call of Duty to skip PlayStation 4 and Xbox One.

From BBC May 29, 2026

“We’ve made it kind of core to who Allegiant is to seek out opportunities that aren’t typically served by mainline carriers,” said Drew Wells, the airline’s chief commercial officer.

From The Wall Street Journal May 17, 2026

Of a student body of 5,700, about 400 participate in one of three evangelical student groups—more than the number of active mainline Protestants, the campus chaplain says.

From "Class Matters" by The New York Times

More than 30% of DWP’s mainlines are more than 80 years old and at least 6% of them are considered high priority for replacement.

From Los Angeles Times Jul. 25, 2026

"There is still no commitment to electrifying the north Wales or south Wales mainlines, something businesses consistently tell us is essential to unlocking real economic growth across the whole country."

From BBC Feb. 17, 2026

He mainlines all of his romantic entanglements as if they were the antidote to his unresolved traumas.

From Salon Apr. 25, 2025

The line was used to transport agricultural products and produce as a crucial connector to other mainlines down the Columbia River.

From Seattle Times Sep. 7, 2023

Current labor agreements ensure that freight trains on mainlines have two people — an engineer and conductor — onboard.

From Washington Post Mar. 3, 2023

But the show still went on that night, thanks to Voytko, a swing and an understudy for Marian, who mainlined the role in eight hours.

From New York Times Feb. 2, 2022

Johnson said that businesses had mainlined on low-wage imported labour for nearly 25 years and that they should now pay their workers more and invest more.

From Reuters Oct. 5, 2021

“Hades,” because you can really get in the zone on that game, and they’ve got the meta-upgrade drug mainlined right to your brain: So.

From Los Angeles Times May 5, 2020

I mean, they’re really being mainlined right into your brain.

From Washington Post Oct. 15, 2018

It is less a video game than mainlined anxiety, its jump-scares timed with sadistic precision and its long, shadow-splashed corridors masterpieces of unnerving light design.

From Slate Feb. 1, 2011

The ubiquity of holiday songs also represents a rare monocultural music moment—even though listeners are spread across multiple streaming services and social-media platforms, many of them are mainlining the same tunes.

From The Wall Street Journal Dec. 14, 2025

In some ways, I feel like a conspiracy junkie who has relapsed, mainlining paranoia and dread.

From Salon Jul. 17, 2024

Sheek Louch, who sounds like he’s been mainlining Ka records, has an excellent verse on “Donda.”

From New York Times Aug. 31, 2021

‘Ready Player One’ feels like mainlining the VH1 show ‘I Love the ’80s.’

From Washington Post Jul. 14, 2021

Youths, I am told, speak of “hopium” and “copium,” but we need a word that incorporates the never-ending mainlining of information as well as the positive or negative cast of that information.

From Slate Nov. 6, 2020

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