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Synonyms

poisonous

American  
[poi-zuh-nuhs] / ˈpɔɪ zə nəs /

adjective

  1. full of or containing poison.

    poisonous air; a poisonous substance.

  2. harmful; destructive.

    poisonous to animals; poisonous rumors.

  3. deeply malicious; malevolent.

    poisonous efforts.


poisonous British  
/ ˈpɔɪzənəs /

adjective

  1. having the effects or qualities of a poison

  2. capable of killing or inflicting injury; venomous

  3. corruptive or malicious

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of poisonous

First recorded in 1565–75; poison + -ous

Compare meaning

How does poisonous compare to similar and commonly confused words? Explore the most common comparisons:

Explanation

What do arsenic, cyanide, and bleach all have in common? They're poisonous. In other words, if you ingest these poisonous chemicals, you will most likely die or become very ill. If something is poisonous, you'd better not eat, drink, inhale, or touch it: it will make you sick. Some poisonous materials can even kill you. Of course, this adjective is derived from the noun poison, which is a toxic substance. You can also calls things poisonous if they're harmful in less physical ways. Spreading lies about someone is poisonous. Betraying a friend is poisonous. What both kinds of poisonous things have in common is that they do damage.

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Vocabulary lists containing poisonous

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Three people were recently hospitalized after eating poisonous wild mushrooms foraged in California wine country amid an unprecedented outbreak of illness and deaths linked to the practice statewide, health officials in Napa County announced.

From Los Angeles Times • May 15, 2026

In this poisonous time, those who grin at the notion of playing a Traitor may think twice about the potential cost to their principles.

From Salon • Jan. 28, 2026

But time and again the poisonous isolation that absolute power imposes on its wielders blunted the edge of their insight and degraded the capacity of their societies.

From The Wall Street Journal • Jan. 26, 2026

Whether you have sympathy for him, think his behaviour is appalling, or something in between, there's clearly a poisonous row raging over what he did.

From BBC • Jan. 17, 2026

We nomads live in an area with dangerous animals and poisonous snakes.

From "Facing the Lion" by Joseph Lemasolai Lekuton and Herman Viola

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