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Synonyms

poisonous

American  
[poi-zuh-nuhs] / ˈpɔɪ zə nəs /

adjective

  1. full of or containing poison.

    poisonous air; a poisonous substance.

  2. harmful; destructive.

    poisonous to animals; poisonous rumors.

  3. deeply malicious; malevolent.

    poisonous efforts.


poisonous British  
/ ˈpɔɪzənəs /

adjective

  1. having the effects or qualities of a poison

  2. capable of killing or inflicting injury; venomous

  3. corruptive or malicious

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

  • nonpoisonous adjective
  • nonpoisonously adverb
  • nonpoisonousness noun
  • poisonously adverb
  • poisonousness noun
  • semipoisonous adjective
  • semipoisonously adverb
  • unpoisonous adjective
  • unpoisonously adverb

Etymology

Origin of poisonous

First recorded in 1565–75; poison + -ous

Compare meaning

How does poisonous compare to similar and commonly confused words? Explore the most common comparisons:

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

It’s got poisonous lead in it from paint.

From Salon • Mar. 6, 2026

Hydrogen cyanide, which is highly poisonous, can freeze into crystals at low temperatures.

From Science Daily • Jan. 16, 2026

There’s no silver bullet for finding out whether a wild mushroom is poisonous unless you know what species it is, said Rudy Diaz, president of the Los Angeles Mycological Society.

From Los Angeles Times • Dec. 10, 2025

Perhaps, but it also gave an immediacy bordering on desperation to a story of teenage identity, poisonous social media and murder.

From The Wall Street Journal • Nov. 24, 2025

Who knew better how poisonous the soil was in Weep than she who had been poisoning it for ten long years?

From "Strange the Dreamer" by Laini Taylor