[pree-dis-puh-zish-uh n, pree-dis-]
See more synonyms for predisposition on
  1. the fact or condition of being predisposed: a predisposition to think optimistically.
  2. Medicine/Medical. tendency to a condition or quality, usually based on the combined effects of genetic and environmental factors.

Origin of predisposition

First recorded in 1615–25; pre- + disposition
Related formspre·dis·po·si·tion·al, adjective Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

Examples from the Web for predisposition

Contemporary Examples of predisposition

Historical Examples of predisposition

  • Laws must be definite, and we should create in the citizens a predisposition to obey them.



  • There has been a predisposition to paralysis, which is the true nature of this attack.

    Rim o' the World

    B. M. Bower

  • In every member of it he recognised character, and a predisposition which might even be genius.


    Benjamin Disraeli

  • She understood not how fatal a predisposition lurked in her bosom.

  • Their views rather wearied me, despite my predisposition to favour them.

    The Message

    Alec John Dawson

British Dictionary definitions for predisposition


  1. the condition of being predisposed
  2. med susceptibility to a specific diseaseSee diathesis
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for predisposition

1620s, from pre- + disposition.

Online Etymology Dictionary, © 2010 Douglas Harper

predisposition in Medicine


  1. The state of being predisposed.
  2. A condition of special susceptibility, as to a disease.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.