[pree-dis-puh-zish-uh n, pree-dis-]


the fact or condition of being predisposed: a predisposition to think optimistically.
Medicine/Medical. tendency to a condition or quality, usually based on the combined effects of genetic and environmental factors.

Origin of predisposition

First recorded in 1615–25; pre- + disposition
Related formspre·dis·po·si·tion·al, adjective Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

Examples from the Web for predisposition

Contemporary Examples of predisposition

Historical Examples of predisposition

  • Laws must be definite, and we should create in the citizens a predisposition to obey them.



  • There has been a predisposition to paralysis, which is the true nature of this attack.

    Rim o' the World

    B. M. Bower

  • In every member of it he recognised character, and a predisposition which might even be genius.


    Benjamin Disraeli

  • She understood not how fatal a predisposition lurked in her bosom.

  • Their views rather wearied me, despite my predisposition to favour them.

    The Message

    Alec John Dawson

British Dictionary definitions for predisposition



the condition of being predisposed
med susceptibility to a specific diseaseSee diathesis
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for predisposition

1620s, from pre- + disposition.

Online Etymology Dictionary, © 2010 Douglas Harper

predisposition in Medicine




The state of being predisposed.
A condition of special susceptibility, as to a disease.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.