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irritate

American  
[ir-i-teyt] / ˈɪr ɪˌteɪt /

verb (used with object)

irritated, irritating
  1. to excite to impatience or anger; annoy.

    Synonyms:
    inflame, infuriate, enrage, incense, pic, ruffle, nettle, gall, fret, chafe, vex
  2. Physiology, Biology. to excite (a living system) to some characteristic action or function.

  3. Pathology. to bring (a body part) to an abnormally excited or sensitive condition.


verb (used without object)

irritated, irritating
  1. to cause irritation or become irritated.

irritate British  
/ ˈɪrɪˌteɪt /

verb

  1. to annoy or anger (someone)

  2. (tr) biology to stimulate (an organism or part) to respond in a characteristic manner

  3. (tr) pathol to cause (a bodily organ or part) to become excessively stimulated, resulting in inflammation, tenderness, etc

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Related Words

Irritate, exasperate, provoke mean to annoy or stir to anger. To irritate is to excite to impatience or angry feeling, often of no great depth or duration: to irritate by refusing to explain an action. To exasperate is to irritate to a point where self-control is threatened or lost: to exasperate by continual delays and excuses. To provoke is to stir to a sudden, strong feeling of resentful anger as by unwarrantable acts or wanton annoyance: to tease and provoke an animal until it attacks.

Other Word Forms

  • irritator noun

Etymology

Origin of irritate

1525–35; < Latin irrītātus, past participle of irrītāre to arouse to anger, excite, aggravate, equivalent to irritā- v. stem + -tus past participle suffix

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

In larger amounts, it can also irritate the body, sometimes leading to skin rashes or digestive discomfort.

From Science Daily • Jan. 17, 2026

For more complicated products or ones with ingredients that can irritate the skin if they're not formulated correctly, such as retinols or vitamin C, Dr Bhate recommends sticking to more specialised brands.

From BBC • Dec. 13, 2025

Failing to pass the package would create uncertainty for Tesla shareholders and likely irritate Musk.

From Barron's • Oct. 30, 2025

Whatever it is will offer plenty to irritate us.

From The Wall Street Journal • Oct. 21, 2025

As for my parents, boy, do they think my every move is a deliberate plan to irritate them.

From "The Freedom Writers Diary" by The Freedom Writers